N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5

Product Name: N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5
CAS No.: 2107273-42-5
Chemical Name: N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5
Synonyms: N-(azide-PEG3)-N'-(PEG4-acid)-Cy5
CBNumber: CB28054764
Molecular Formula: C44H62ClN5O9
Formula Weight: 840.46
MOL File: 2107273-42-5.mol

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N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 Property

solubility: Soluble in Water, DMSO, DMF, DCM

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23029
Product name: N-(azide-PEG3)-N'-(PEG4-acid)-Cy5
Purity: 96%
Packaging: 1mg
Price: $245
Updated: 2021/12/16

BroadPharm

Product number: BP-23029
Product name: N-(azide-PEG3)-N'-(PEG4-acid)-Cy5
Purity: 96%
Packaging: 5mg
Price: $680
Updated: 2021/12/16

BroadPharm

Product number: BP-23029
Product name: N-(azide-PEG3)-N'-(PEG4-acid)-Cy5
Purity: 96%
Packaging: 10mg
Price: $1020
Updated: 2021/12/16

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N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 Chemical Properties,Usage,Production

Description

N-(azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm and a free terminal carboxyl acid. Terminal carboxylic acid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydophilic PEG spacer increases solubility in aqueous media.

Uses

N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 Suppliers

China 7 United States 2 Global 9

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2107273-42-5, N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5Related Search:

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N-(azide-PEG3)-N'-(PEG4-acid)-Cy5

2107273-42-5