Afamelanotide acetate

Product Name: Afamelanotide acetate
CAS No.: 1566590-77-9
Chemical Name: Afamelanotide acetate
Synonyms: Afamelanotide acetate;Afamelanotide acetate, 10 mM in DMSO;(Nle4,D-Phe7)-α-MSHAfaMelanotide, NDP-MSH, Melanotan 1, CUV1647
CBNumber: CB28054870
Molecular Formula: C80H115N21O21
Formula Weight: 1706.93
MOL File: 1566590-77-9.mol

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

Afamelanotide acetate Chemical Properties,Usage,Production

Uses

Afamelanotide promotes skin pigmentation and provides protection from the sun. In dermatology, afamelanotide appears to be effective in treating polymorphic light eruption, solar urticaria, erythropoietic protoporphyria (EPP), Heili-Heili disease, vitiligo, and acne vulgaris. Afamelanotide may also be used non-medically to achieve quick and easy skin tanning^[2].

General Description

Afamelanotide, a synthetic α-melanocyte stimulating hormone analog and first-in-class melanocortin-1 receptor agonist, has been approved in the EU for the prevention of phototoxicity in adults with erythropoietic protoporphyria (EPP)^[1].

Side effects

Common adverse reactions to afamelanotide include headache and implant site reactions. Other adverse reactions include the development and aggravation of melanocytic nevi, degeneration of melanocytic nevi into melanoma, dark spots, systemic toxicity, rhabdomyolysis, posterior reversible encephalopathy syndrome, acromegaly, and oral soft tissue pigmentation. In addition, dentists should be alert to oral soft tissue pigmentation caused by afamelanotide^[2].

References

[1] ESTHER S. KIM; Karly P G J. Afamelanotide: A Review in Erythropoietic Protoporphyria[J]. American Journal of Clinical Dermatology, 2016, 17 2: 179-185. DOI:10.1007/s40257-016-0184-6.
[2] C DE BAAT. [Medicaments and oral healthcare. Hyperpigmentation of oral soft tissues due to afamelanotide].[J]. Nederlands tijdschrift voor tandheelkunde, 2020, 127 4: 237-243. DOI:10.5177/ntvt.2020.04.19115.

Afamelanotide acetate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Afamelanotide acetate Suppliers

China 18 United States 2 Global 20

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1011
Advantage: 55

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6312
Advantage: 58

Shanghai Luofa Biochemical Technology Co., Ltd.

Tel: 021-51111890 15317326293
Email: sales@molnova.com
Country: China
ProdList: 4195
Advantage: 58

Sichuan Taihui Biotechnology Co., Ltd

Tel: 028-87189093 18599944286
Email: 272503470@qq.com
Country: China
ProdList: 99
Advantage: 58

Nanjing Yuanpeptide Biotech Co.，Ltd.

Tel: 18168071971
Email: support@yuan-peptide.com
Country: China
ProdList: 2981
Advantage: 58

Chengdu Jinglin Biotechnology Co., Ltd.

Tel: 17711399154
Email: 3211919385@qq.com
Country: China
ProdList: 1815
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd

Tel: 18049165724 13186333400
Email: cuichengbio@163.com
Country: China
ProdList: 4080
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

Taiyuan Bailihengkang Biotechnology Co., Ltd

Tel: 19135651983 19135651983
Email: 18611134419@163.com
Country: China
ProdList: 4416
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: sangon@qq.com
Country: China
ProdList: 47240
Advantage: 58

American HealthyMorph LLC

Tel: +8613363867578
Email: 13363867578@163.com
Country: China
ProdList: 152
Advantage: 58

Jinan Million Pharmaceutical Co., Ltd

Tel: 0531-68659554 +8613031714605
Fax: Room1-2208, Gaoxin district, Jinan, Shandong
Email: info@millionpharm.com
Country: China
ProdList: 295
Advantage: 58

Strong peptide cross-border e-commerce Co. LTD

Tel: +undefined13930052870
Email: qt01@qiangtaipharm.com
Country: China
ProdList: 84
Advantage: 58

Hebei Kangcang new material Technology Co., LTD

Tel: +8615713292910
Email: Nancy@kangcang.com.cn
Country: China
ProdList: 341
Advantage: 58

Nantong Guangyuan Chemicl Co,Ltd

Tel: +undefined17712220823
Email: admin@guyunchem.com
Country: China
ProdList: 615
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6743
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

More

Less

View Lastest Price from Afamelanotide acetate manufacturers

Strong peptide cross-border e-commerce Co. LTD

Product: afamelanotide 1566590-77-9
Price: US $40.00-35.00/box
Min. Order: 1box
Purity: 99.9+
Supply Ability: 2000box
Release date: 2024-05-28

Strong peptide cross-border e-commerce Co. LTD

Product: afamelanotide 1566590-77-9
Price: US $40.00-35.00/box
Min. Order: 1box
Purity: 99.9+
Supply Ability: 2000box
Release date: 2024-05-28

Strong peptide cross-border e-commerce Co. LTD

Product: afamelanotide 1566590-77-9
Price: US $40.00-35.00/box
Min. Order: 1box
Purity: 99.9+
Supply Ability: 2000box
Release date: 2024-05-28

1566590-77-9, Afamelanotide acetateRelated Search:

H-MET-GLU-VAL-GLY-TRP-TYR-ARG-PRO-PRO-PHE-SER-ARG-VAL-VAL-HIS-LEU-TYR-ARG-ASN-GLY-LYS-OH XENOPSIN-RELATED PEPTIDE 1 ANGIOTENSINOGEN (1-14) (RAT) (TRP6)-LHRH GALANIN (2-29) (RAT)

(Nle4,D-Phe7)-α-MSHAfaMelanotide, NDP-MSH, Melanotan 1, CUV1647

Afamelanotide acetate

Afamelanotide acetate, 10 mM in DMSO

1566590-77-9