ChemicalBook > CAS DataBase List > Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
- Product Name
- Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
- CAS No.
- 2225148-51-4
- Chemical Name
- Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
- Synonyms
- JUN 48514;Thalidomide-O-C8-acid;Thalidomide-O-C8-COOH;Thalidomide-4-O-C8-COOH;Thalidomide 4'-ether-alkylC8-acid;9-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]oxynonanoic acid;9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)nonanoic acid;9-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]nonanoic Acid;Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-;9-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)nonanoic acid?, Thalidomide-O-C8-COOH
- CBNumber
- CB28094236
- Molecular Formula
- C22H26N2O7
- Formula Weight
- 430.45
- MOL File
- 2225148-51-4.mol
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Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Property
- form
- Solid
- color
- White to off-white
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Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Chemical Properties,Usage,Production
Biological Activity
Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].
storage
Store at -20°C
References
[1]. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1.
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Thalidomide-O-C8-acid 2225148-51-4
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >96.00%
- Supply Ability
- 100mg
- Release date
- 2024-04-01