PF-06928215

Product Name: PF-06928215
CAS No.: 2378173-15-8
Chemical Name: PF-06928215
Synonyms: PF-06928215;PF-06928215, 10 mM in DMSO;Inhibitor,PF-06928215,cGAS,inhibit,PF 06928215,Cyclic GMP-AMP Synthase,PF06928215;(1R,2S)-2-(7-Hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamido)cyclohexanecarboxylic acid;Cyclohexanecarboxylic acid, 2-[[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)carbonyl]amino]-, (1R,2S)-
CBNumber: CB28096285
Molecular Formula: C20H20N4O4
Formula Weight: 380.4
MOL File: 2378173-15-8.mol

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PF-06928215 Property

storage temp.: Store at -20°C
solubility: DMSO: 30 mg/ml
form: A solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0078781
Product name: PF-06928215
Purity: >99.0%
Packaging: 5mg
Price: $210
Updated: 2021/12/16

CSNpharm

Product number: CSN23557
Product name: PF-06928215
Packaging: 5mg
Price: $200
Updated: 2021/12/16

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PF-06928215 Chemical Properties,Usage,Production

Biological Activity

PF-06928215 is a high-affinity cGAS (cyclic GMP-AMP Synthase) inhibitor with IC50 of 4.9 μM and affinity Kd value of 0.2 μM.

in vitro

PF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression.

PF-06928215 Preparation Products And Raw materials

Raw materials

Preparation Products

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PF-06928215 Suppliers

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2378173-15-8, PF-06928215Related Search:

Cyclohexanecarboxylic acid, 2-[[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)carbonyl]amino]-, (1R,2S)-

PF-06928215

Inhibitor,PF-06928215,cGAS,inhibit,PF 06928215,Cyclic GMP-AMP Synthase,PF06928215

(1R,2S)-2-(7-Hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamido)cyclohexanecarboxylic acid

PF-06928215, 10 mM in DMSO

2378173-15-8