1H-Indazole-3-carboxamide, N-[1-(3,4-difluorophenyl)ethyl]-
- Product Name
- 1H-Indazole-3-carboxamide, N-[1-(3,4-difluorophenyl)ethyl]-
- CAS No.
- 877969-69-2
- Chemical Name
- 1H-Indazole-3-carboxamide, N-[1-(3,4-difluorophenyl)ethyl]-
- Synonyms
- VPC-80051;VPC-80051 racemate;VPC-80051(Racemic);VPC-80051(VPC80051);VPC-80051 racemate, 10 mM in DMSO;N-(1-(3,4-Difluorophenyl)ethyl)-1H-indazole-3-carboxamide;1H-Indazole-3-carboxamide, N-[1-(3,4-difluorophenyl)ethyl]-;Inhibitor,VPC 80051 racemate,VPC-80051,VPC 80051,inhibit,VPC80051,VPC80051 racemate
- CBNumber
- CB28241773
- Molecular Formula
- C16H13F2N3O
- Formula Weight
- 301.29
- MOL File
- 877969-69-2.mol
1H-Indazole-3-carboxamide, N-[1-(3,4-difluorophenyl)ethyl]- Property
- Boiling point:
- 551.3±45.0 °C(Predicted)
- Density
- 1.358±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 12.12±0.46(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
1H-Indazole-3-carboxamide, N-[1-(3,4-difluorophenyl)ethyl]- Chemical Properties,Usage,Production
Uses
VPC-80051 racemate is a racemate of VPC-80051. VPC-80051 is a prototype inhibitor of the hnRNP A1 splicing factor[1].
References
[1] Carabet LA, et al. Computer-Aided Discovery of Small Molecules Targeting the RNA Splicing Activity of hnRNP A1 in Castration-Resistant Prostate Cancer. Molecules. 2019;24(4):763. Published 2019 Feb 20. DOI:10.3390/molecules24040763
1H-Indazole-3-carboxamide, N-[1-(3,4-difluorophenyl)ethyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
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