2,4-DIAMINO-6-ETHOXYPYRIMIDINE

Product Name: 2,4-DIAMINO-6-ETHOXYPYRIMIDINE
CAS No.: 116436-03-4
Chemical Name: 2,4-DIAMINO-6-ETHOXYPYRIMIDINE
Synonyms: Minoxidil Impurity 6;6-Ethoxypyrimidine-2,4-diamine;2,4-Diamino-6-ethoxy-pyrimidin;2,4-DIAMINO-6-ETHOXYPYRIMIDINE;2,4-Pyrimidinediamine, 6-ethoxy-;Terbufos Impurity 2 (Terbufos Sulfoxide);2,4-DIAMINO-6-ETHOXYPYRIMIDINE ISO 9001：2015 REACH
CBNumber: CB2840462
Molecular Formula: C6H10N4O
Formula Weight: 154.17
MOL File: 116436-03-4.mol

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2,4-DIAMINO-6-ETHOXYPYRIMIDINE Property

Melting point:: 160 °C(Solv: water (7732-18-5))
Boiling point:: 420.8±48.0 °C(Predicted)
Density: 1.274±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 5.41±0.10(Predicted)
Appearance: Light yellow to yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: Y4911
Product name: 2,4-Diamino-6-ethoxypyrimidine
Packaging: 250mg
Price: $147
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0117355
Product name: 2,4-DIAMINO-6-ETHOXYPYRIMIDINE
Purity: 95.00%
Packaging: 100G
Price: $3614
Updated: 2021/12/16

Ambeed

Product number: A325552
Product name: 2,4-Diamino-6-ethoxypyrimidine
Purity: 97%
Packaging: 100mg
Price: $35
Updated: 2021/12/16

Ambeed

Product number: A325552
Product name: 2,4-Diamino-6-ethoxypyrimidine
Purity: 97%
Packaging: 250mg
Price: $68
Updated: 2021/12/16

Ambeed

Product number: A325552
Product name: 2,4-Diamino-6-ethoxypyrimidine
Purity: 97%
Packaging: 1g
Price: $153
Updated: 2021/12/16

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2,4-DIAMINO-6-ETHOXYPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

156-83-2

64-17-5

116436-03-4

To a suspension of sodium hydride (2.77 g, 69.2 mmol) in anhydrous ethanol (150 mL) was added 2,4-diamino-6-chloropyrimidine (5.0 g, 34.6 mmol) in batches. The reaction mixture was heated to reflux and kept for 6 hours. After completion of the reaction, it was cooled to room temperature and the reaction solution was neutralized with an isopropanol solution of 5-6 N hydrochloric acid. The solvent was removed by concentration under reduced pressure and the resulting residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol=40:1, v/v) to afford 2,4-diamino-6-ethoxypyrimidine as a white solid (4.0 g, 75% yield). The melting point of the product was 164-165 °C. 1H NMR (300 MHz, DMSO-d6, 25 °C): δ 6.00 (s, 2H, NH2), 5.88 (s, 2H, NH2), 5.03 (s, 1H, CH), 4.13 (q, J=7.1 Hz, 2H, OCH2CH3), 1.22 (t, J=7.1 Hz, 3H OCH2CH3).13C NMR (75 MHz, DMSO-d6, 25°C): δ 170.0 (C), 165.9 (C), 162.9 (C), 76.1 (CH), 60.2 (OCH2CH3), 14.7 (OCH2CH3). High resolution mass spectrometry (HRMS): calculated value C6H11N4O [M+H]+ 155.09329, measured value 155.09260.

References

[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 1, p. 702 - 714
[2] Patent: US2004/77859, 2004, A1. Location in patent: Page 23
[3] Organic and Biomolecular Chemistry, 2010, vol. 8, # 10, p. 2397 - 2407
[4] Journal of the American Chemical Society, 1951, vol. 73, p. 2864,2867
[5] Journal of Organic Chemistry, 2005, vol. 70, # 7, p. 2729 - 2738

2,4-DIAMINO-6-ETHOXYPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DIAMINO-6-ETHOXYPYRIMIDINE Suppliers

China 71 India 1 Switzerland 2 United Kingdom 4 United States 10 Global 88

Adamas Reagent, Ltd.

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Aikon International Limited

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SHANGHAI FDC-CHEMICAL CO.,LTD

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Wuhan FengyaoTonghui Chemical Products Co., Ltd.

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View Lastest Price from 2,4-DIAMINO-6-ETHOXYPYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 2,4-DIAMINO-6-ETHOXYPYRIMIDINE 116436-03-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-13

116436-03-4, 2,4-DIAMINO-6-ETHOXYPYRIMIDINERelated Search:

6-Benzyloxy-5-nitroso-pyrimidine-2,4-diamine 2-Amino-4-isopropoxy-6-(methylamino)-5-nitroso-pyrimidine 4-CYCLOHEXYLMETHOXY-2,6-DIAMINO-5-NITROSOPYRIMIDINE N-[4-(2,6-Diamino-pyrimidin-4-yloxymethyl)-benzyl]-2,2,2-trifluoro-acetamide 2,4-BIS(ACRYLAMIDO)-6-ETHOXYPYRIMIDINE 2,4-diamino-6-(benzyloxy)pyrimidine-5-carbonitrile 2,4-diamino-6-ethoxy-5-pyrimidinecarbonitrile N-[4-AMINO-5-NITROSO-6-(PENTYLOXY)PYRIMIDIN-2-YL]-N-METHYLAMINE 2,4-DIAMINO-6-ETHOXYPYRIMIDINE

2,4-DIAMINO-6-ETHOXYPYRIMIDINE

2,4-Diamino-6-ethoxy-pyrimidin

6-Ethoxypyrimidine-2,4-diamine

Minoxidil Impurity 6

2,4-Pyrimidinediamine, 6-ethoxy-

2,4-DIAMINO-6-ETHOXYPYRIMIDINE ISO 9001：2015 REACH

Terbufos Impurity 2 (Terbufos Sulfoxide)

116436-03-4