R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATE

Product Name: R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATE
CAS No.: 164456-75-1
Chemical Name: R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATE
Synonyms: R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATE;Methyl (R)-1-Boc-2-piperidinecarboxylate;Methyl (R)-1-Boc-piperidine-2-carboxylate;Boc-R-piperidine-2-carboxylic acid Methyl ester;Boc-D-piperidine-2-carboxylic acid Methyl ester;1-(R)-tert-butyl 2-methyl piperidine-1,2-dicarboxylate;(R)-1-tert-Butyl 2-Methyl piperidine-1,2-dicarboxylate;1-tert-butyl 2-Methyl (2R)-piperidine-1,2-dicarboxylate;1-O-tert-butyl 2-O-methyl (2R)-piperidine-1,2-dicarboxylate;1,2-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) 2-methyl ester, (2R)-
CBNumber: CB2841782
Molecular Formula: C12H21NO4
Formula Weight: 243.3
MOL File: Mol file

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R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATE Property

Boiling point:: 307.4±35.0 °C(Predicted)
Density: 1.094±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: -3.28±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CCH0030199
Product name: R-METHYL-1-BOC-PIPERIDINE-2-CARBOXYLATE
Purity: 95.00%
Packaging: 1G
Price: $262.5
Updated: 2021/12/16

Activate Scientific

Product number: AS86003
Product name: Methyl (R)-1-Boc-2-piperidinecarboxylate
Purity: 95+% ee
Packaging: 5G
Price: $652
Updated: 2021/12/16

Ambeed

Product number: A207555
Product name: (R)-1-tert-Butyl2-methylpiperidine-1,2-dicarboxylate
Purity: 95+%
Packaging: 250mg
Price: $41
Updated: 2021/12/16

Ambeed

Product number: A207555
Product name: (R)-1-tert-Butyl2-methylpiperidine-1,2-dicarboxylate
Purity: 95+%
Packaging: 100mg
Price: $41
Updated: 2021/12/16

Chemenu

Product number: CM180134
Product name: 1-(tert-butyl)2-methyl(R)-piperidine-1,2-dicarboxylate
Purity: 95%
Packaging: 1g
Price: $143
Updated: 2021/12/16

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R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

28697-17-8

74-88-4

164456-75-1

General steps: 1. In a dry reaction flask, (R)-1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid (5.1 g, 22.2 mmol) was dissolved in DMF (60 mL). 2. K2CO3 (12.3 g, 88.8 mmol) and iodomethane (1.7 mL, 26.6 mmol) were added sequentially to the above solution. 3. The reaction mixture was stirred at room temperature overnight. 4. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate. 5. The organic layer was separated and washed 6 times with distilled water and once with saturated saline. 6. The organic layer was dried over anhydrous Na2SO4, filtered and concentrated to give methyl (R)-N-Boc-piperidine-2-carboxylate (5.4 g, 99% yield). 7. The product was characterized by 1H NMR (300 MHz, CDCl3): δ 4.82 (m, 1H), 3.99 (m, 1H), 3.75 (s, 3H), 2.95 (m, 1H), 2.21 (m, 1H), 2.45 (m, 14H).

References

[1] Patent: US2007/259916, 2007, A1. Location in patent: Page/Page column 9
[2] Patent: US2007/259862, 2007, A1. Location in patent: Page/Page column 10
[3] Patent: US2004/198701, 2004, A1. Location in patent: Page/Page column 10
[4] Patent: US2005/227969, 2005, A1. Location in patent: Page/Page column 10

R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATE Suppliers

China 22 India 1 United States 2 Global 25

Shanghai Boyle Chemical Co., Ltd.

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164456-75-1, R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATERelated Search:

R-METHYL 1-BOC-PIPERIDINE-2-CARBOXYLATE

1-tert-butyl 2-Methyl (2R)-piperidine-1,2-dicarboxylate

Boc-D-piperidine-2-carboxylic acid Methyl ester

Boc-R-piperidine-2-carboxylic acid Methyl ester

(R)-1-tert-Butyl 2-Methyl piperidine-1,2-dicarboxylate

Methyl (R)-1-Boc-2-piperidinecarboxylate

1-(R)-tert-butyl 2-methyl piperidine-1,2-dicarboxylate

1,2-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) 2-methyl ester, (2R)-

Methyl (R)-1-Boc-piperidine-2-carboxylate

1-O-tert-butyl 2-O-methyl (2R)-piperidine-1,2-dicarboxylate

164456-75-1