(S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID
- Product Name
- (S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID
- CAS No.
- 14590-53-5
- Chemical Name
- (S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID
- Synonyms
- (S)-(+)-DMCPCA;Dimethylcyclopropanecarboxylic acid;(S)-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID;(+)-2,2-Dimethylcyclopropanecarboxylic acid;(S)-2,2-Dimethyl cycolpropanecarboxylic acid;(S)-2,2-dimethylcyclopropane-1-carboxylic acid;(1S)-2,2-dimethylcyclopropane-1-carboxylic acid;(S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID;Cyclopropanecarboxylic acid, 2,2-dimethyl-, (1S)-;(S)-(+)-2,2-DimethylcyclopropanecarboxylicAcid>
- CBNumber
- CB2848473
- Molecular Formula
- C6H10O2
- Formula Weight
- 114.14
- MOL File
- 14590-53-5.mol
(S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID Property
- Boiling point:
- 100 °C / 12mmHg
- Density
- 0.99
- refractive index
- 124 ° (C=1, MeOH)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.99±0.22(Predicted)
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2916200090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D3677
- Product name
- (S)-(+)-2,2-Dimethylcyclopropanecarboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $63
- Updated
- 2025/07/31
- Product number
- D3677
- Product name
- (S)-(+)-2,2-Dimethylcyclopropanecarboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $204
- Updated
- 2025/07/31
- Product number
- D477903
- Product name
- (S)-(+)-2,2-Dimethylcyclopropanecarboxylic Acid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- D477903
- Product name
- (S)-(+)-2,2-Dimethylcyclopropanecarboxylic Acid
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 39529
- Product name
- (S)-(+)-2,2-Dimethylcyclopropanecarboxylicacid,≥98%(Assaybytitration,GC)
- Purity
- ≥98%(Assaybytitration,GC)
- Packaging
- 1G
- Price
- $59.4
- Updated
- 2021/12/16
(S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
645413-67-8
14590-53-5
General procedure for the synthesis of (S)-(+)-2,2-dimethylcyclopropanecarboxylic acid from 2,2,2-difluorocyclopropanecarboxylic acid 2,2-difluoroethyl ester (60 g): in a 2L round-bottomed flask equipped with a stirrer, a pH meter, and a thermometer, 2,2,2-difluorocyclopropanecarboxylic acid 2,2-difluoroethyl ester (60 g), potassium hydrogen phosphate (2 mg) and water (600 mL) were added. Esterase (CLS-BC-21012, 1.5 g) was added to the reaction mixture and the reaction temperature was maintained at 40 °C. The pH of the reaction system was adjusted to 7.0 using 50% aqueous sodium bicarbonate.After the reaction was completed, the esterase was removed by filtration through filter paper, and 35% hydrochloric acid was slowly added to the filtrate to adjust the pH to 2.0.Subsequently, ethyl acetate (600 mL) was added to the mixture, and it was stirred for 15 min. The organic and aqueous phases were separated, and the organic phase was distilled to recover the solvent and low-boiling organics to afford (S)-(+)-2,2-dimethylcyclopropanecarboxylic acid (Yield: 49.1%, Purity: 99.0%, Optical purity: 99.1%). tlc Rf = 0.5 (n-hexane/ethyl acetate, 2:1). 1H NMR (CDCl3, 300MHz) δ: 1.55 ( dd, 1H, J = 7.95Hz, J = 5.42Hz), 1.19 (s, 3H), 1.16 (s, 3H), 1.13 (dd, 1H, J = 4.98Hz, J = 4.89Hz), 0.92 (dd, 1H, J = 7.98Hz, J = 4.42Hz).
References
[1] Patent: WO2004/5241, 2004, A1. Location in patent: Page 9-10
(S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 847-367-3680
- Fax
- 847-367-3681
- sales@arkpharminc.com
- Country
- United States
- ProdList
- 1670
- Advantage
- 56
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9883
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 6387
- Advantage
- 52
- Tel
- 025-66113011 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19913
- Advantage
- 55
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
View Lastest Price from (S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID manufacturers
- Product
- (S)-(+)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID 14590-53-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-08