ChemicalBook > CAS DataBase List > cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate

cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate

Product Name
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
CAS No.
134071-44-6
Chemical Name
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
Synonyms
CIS-TOSYLATE;Active Ester;Activity Ester;K6 / Cis Tosylate;oxymethyl-1,3-dioxolane;Ketoconazole IMpurity E;KETOCOZOLE EP IMPURITY E;Ketoconazole EP Impurity E;ACTIVE ESTER OF KETOCONZOL;Activity Esterof Ketoconazo
CBNumber
CB2855192
Molecular Formula
C21H20Cl2N2O5S
Formula Weight
483.36
MOL File
134071-44-6.mol
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cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Property

Melting point:
120-122°C
Boiling point:
665.7±55.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
6.88±0.12(Predicted)
color 
White to Off-White
CAS DataBase Reference
134071-44-6(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D435718
Product name
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methylp-Tolylsulfonate
Packaging
2g
Price
$255
Updated
2021/12/16
TRC
Product number
D435718
Product name
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methylp-Tolylsulfonate
Packaging
10g
Price
$1070
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21680
Product name
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-tolylsulfonate
Packaging
10g
Price
$1280
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0000074
Product name
(2R,4R) CIS-(2,4-DICHLOROPHENYL)-2-(1,2,4-TRIAZOLE-1-YL-METHYL)-1,3-DIOXOLANE-4YL-METHYL-P-TOLYSULFONATE
Purity
95.00%
Packaging
10G
Price
$2055.9
Updated
2021/12/16
AK Scientific
Product number
B606
Product name
CIS-Tosylate
Packaging
1g
Price
$131
Updated
2021/12/16
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cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate (Ketoconazole EP Impurity E) is an intermediate in the synthesis of the drug Ketoconazole (K186000).

cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Preparation Products And Raw materials

Raw materials

Preparation Products

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cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Suppliers

Conier Chem & Pharma Co.,Ltd,
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023-62879767 13996269627;
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+86-28-84559521
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sales@conier.com
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China
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Shanghai Qiao Chemical Science Co., Ltd
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021-58892003
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info@qiaochem.com
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China
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BTC Pharmaceutical CO. Ltd
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0513-0513-68015397 18862996710
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0513-68015394
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sales12@btcpharm.com
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China
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Shanghai Taijilin Industrial Co., Ltd.
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021-021-50630626 18964684208
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021-50563898
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kate@tajilin.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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0573-85285100
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isenchem@163.com
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China
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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chenyj@titansci.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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China
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Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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XiaoGan ShenYuan ChemPharm co,ltd
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15527768850
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1791901229@qq.com
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China
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View Lastest Price from cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate manufacturers

Qiuxian Baitai New Material Co., LTD
Product
Cis - (2 - (2, 4 - dichlorobenzene) - 2 - (1 h - imidazole 1 - methyl) - 1, 3 - dioxolane - 4 - base) methanol p-toluene sulfonic acid ester 134071-44-6
Price
US $2.00/g
Min. Order
1KG
Purity
99%
Supply Ability
5ton/Month
Release date
2021-12-21
Career Henan Chemical Co
Product
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate 134071-44-6
Price
US $1.00/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-24

134071-44-6, cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonateRelated Search:


  • cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
  • CIS-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOLE-1-YL)METHYL-4-(P-TOLUENE SULFONYLOXY) METHYL-1,3-DIOXALANE
  • CIS-[2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-YL METHYL)-1,3-DIOXOLANE-4-YL]-P-METHYLBENZENE SULFONATE
  • CIS-TOSYLATE
  • ACTIVITY ESTEROF KETOCONAZOL
  • CIS-[2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-YL METHYL)-1,3-DIOXOLANE-4-YL]-P-METHYLBENZENE SULFONATE OR -P-METHYL SULFONATE (KETOCONAZLE INTERMEDIATE)
  • Ketoconazole EP Impurity E
  • Cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-l-ylmethyl)- 1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate (CisTosylate)
  • Ketoconazole Impurity 5(Ketoconazole EP Impurity E)
  • 2-[[2-(2,4-dichlorophenyl)-2-(1-imidazolylmethyl)-1,3-dioxolan-4-yl]methyl]-4-methylbenzenesulfonate
  • CIS-2-(2 4- DICHLOROPHENYL)-2-(1-H-IMIDA ZOLE-YL-METHYL) -1 3-DIOXOLAN-4-YL] METH YL-4-METHYLBENZENESULPHONATE
  • CIS-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOLE-1-YL)METHYL-4-(P-TOLUENESULFONYLOXY)METHYL-1,3-DIOXALANE
  • Cis-Tosylate(Cis-2-Dichlorophenyl)2-(Ih-Imidazole-1-Yl)Methyl-4-(P-TolueneSulfonyloxy)Methyl-1,3-Dioxalane
  • CIS-[2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHYL-4-TOLYLSULFONATE
  • Active Ester
  • 1,3-Dioxolane-4-Methanol,2-(2,4-dichlorophenyl)-2-(1H-iMidazol-1-ylMethyl)-,4-(4-Methylbenzenesulfonate), (2R,4R)-rel-
  • (2R,4R)-rel-2-(2,4-Dichlorophenyl)-2-(1H-iMidazol-1-ylMethyl)-1,3-dioxolane-4-Methanol 4-(4-Methylbenzenesulfonate)
  • CIS-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOLE-1-YL)METHYL-4-(P-TOLUENE SUIFONYLOXY)METHYL-1,3-
  • Cis-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1yl-methyl)-4-(p-toluensulfonyl)
  • oxymethyl-1,3-dioxolane
  • (Z)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-ylmeth
  • (cis-2-((1H-IMidazol-1-yl)Methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)Methyl 4-Methylbenzenesulfonate
  • Ketoconazole IMpurity E
  • Activity Esterof Ketoconazo
  • Activity Ester
  • ((2R,4R)-rel-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate
  • (cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenz
  • CIS-TOSYLATE, CIS-[2-2,4-DICHLOROPHENYL]-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHYL-4-METHYLBENZENESULPHONATE
  • (2R,4R) CIS-(2,4-DICHLOROPHENYL)-2-(1,2,4-TRIAZOLE-1-YL-METHYL)-1,3-DIOXOLANE-4YL-METHYL-P-TOLYSULFONATE
  • CIS-[2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXALAN-4-YL]METHYL-P-TOLYSULFONATE
  • (cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzene
  • Cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate (134071-44-6)
  • [(2RS,4SR)-2-(2,4-Dichlorophenyl)-2
  • CIS TOSYLATE : Cis-2-(2,4-Dichlorophenyl)-2-(1H-Imidazole-1-yl)Methyl)-4-(p-Toluene Sulfonyloxy)methyl-1,3-Dioxalane)
  • ACTIVE ESTER OF KETOCONZOL
  • Cis - (2 - (2, 4 - dichlorobenzene) - 2 - (1 h - imidazole 1 - methyl) - 1, 3 - dioxolane - 4 - base) methanol p-toluene sulfonic acid ester
  • cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-d...
  • cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
  • K6 / Cis Tosylate
  • [(2RS,4SR)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate
  • KETOCOZOLE EP IMPURITY E
  • Cis-(2-(2,4-Dichlorophenyl)-2-(lH- Imidazot-1- yl-Methyl)-1,3- Dioxolan-4-yl}methyl-4-Methanol
  • CIS-[2-2,4-DICHLOROPHENYL-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4YL]METHYL-4-METHYLBENZENESULPHONATE(Cis Tosylate)
  • Ketoconazole Intermediate 1e
  • (cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesul
  • 134071-44-6
  • 124071-44-6
  • C21H20Cl2N2O5S
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocycles
  • Intermediates
  • Sulfur & Selenium Compounds
  • Pharmaceutical Intermediates