AZD-0780

Product Name: AZD-0780
CAS No.: 2455427-91-3
Chemical Name: AZD-0780
Synonyms: AZD-0780;PCSK9-IN-12;Laroprovstat;AZD0780(PCSK9-IN-12);AZD0780, 10 mM in DMSO;6'-(((1S,3S)-3-((5-(Difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-one;6'-(((1S,3S)-3-((5-(Difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-one;[1(2H),3'-Bipyridin]-2-one, 6'-[[(1S,3S)-3-[[5-(difluoromethoxy)-2-pyrimidinyl]amino]cyclopentyl]amino]-
CBNumber: CB28941286
Molecular Formula: C20H20F2N6O2
Formula Weight: 414.41
MOL File: 2455427-91-3.mol

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AZD-0780 Property

Boiling point:: 658.4±65.0 °C(Predicted)
Density: 1.434±0.06 g/cm3(Predicted)
pka: 5.92±0.10(Predicted)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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AZD-0780 Chemical Properties,Usage,Production

Uses

PCSK9-IN-12 is a heteroaryl compound. PCSK9-IN-12 has bind affinity for PCSK9 with a Kd value of ＜200 nM. PCSK9-IN-12 can be used for the research of cholesterol metabolism[1].

References

[1] Michael H. Serrano-Wu, et al. Pcsk9 inhibitors and methods of use thereof. Patent. WO2020150474A1.

AZD-0780 Preparation Products And Raw materials

Raw materials

Preparation Products

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AZD-0780 Suppliers

China 32 United States 1 Global 33

Shanghai Lollane Biological Technology Co.,Ltd.

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2455427-91-3, AZD-0780Related Search:

AZD-0780

[1(2H),3'-Bipyridin]-2-one, 6'-[[(1S,3S)-3-[[5-(difluoromethoxy)-2-pyrimidinyl]amino]cyclopentyl]amino]-

PCSK9-IN-12

6'-(((1S,3S)-3-((5-(Difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-one

AZD0780(PCSK9-IN-12)

AZD0780, 10 mM in DMSO

6'-(((1S,3S)-3-((5-(Difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-one

Laroprovstat

2455427-91-3