N,N,2-trimethylquinolin-6-amine
- Product Name
- N,N,2-trimethylquinolin-6-amine
- CAS No.
- 92-99-9
- Chemical Name
- N,N,2-trimethylquinolin-6-amine
- Synonyms
- 6-DIMETILAMINOQUINALDINE;6 Dimethylamino quinaldin;6-DIMETHYLAMINOQUINALDINEM;N,N,2-trimethylquinolin-6 mine;N,N,2-Trimethyl-6-quinolinamine;N,N,2-trimethylquinolin-6-amine;6-Quinolinamine, N,N,2-trimethyl-;6-Dimethylamino-2-methylquinoline;N,N,2-trimethylquinolin-6-amine ISO 9001：2015 REACH
- CBNumber
- CB2912163
- Molecular Formula
- C12H14N2
- Formula Weight
- 186.25
- MOL File
- 92-99-9.mol
N,N,2-trimethylquinolin-6-amine Property
- Melting point:
- 101°C
- Boiling point:
- 310.75°C (rough estimate)
- Density
- 1.0859 (rough estimate)
- refractive index
- 1.6648 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 6.58±0.43(Predicted)
- Appearance
- Light yellow to yellow Solid
- EPA Substance Registry System
- 6-Quinolinamine, N,N,2-trimethyl- (92-99-9)
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S648744
- Product name
- 6-DIMETHYLAMINOQUINALDINE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $185
- Updated
- 2025/07/31
- Product number
- S648744
- Product name
- 6-DIMETHYLAMINOQUINALDINE
- Purity
- Aldrich
- Packaging
- 250mg
- Price
- $179
- Updated
- 2024/03/01
- Product number
- 3H32-1-GV
- Product name
- N,N,2-Trimethylquinolin-6-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $952
- Updated
- 2021/12/16
- Product number
- OR945425
- Product name
- N,N,2-Trimethylquinolin-6-amine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $235
- Updated
- 2021/12/16
- Product number
- 3H32-1-GV
- Product name
- N,N,2-Trimethylquinolin-6-amine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $376
- Updated
- 2021/12/16
N,N,2-trimethylquinolin-6-amine Chemical Properties,Usage,Production
Synthesis
123-73-9
99-98-9
92-99-9
4-Amino-N,N-dimethylaniline (10.00 g, 73.4 mmol, source: Alfa Aesar) was dissolved in 6 M aqueous hydrochloric acid solution (132 mL). To this solution was added (E)-2-butenal (10.30 g, 147 mmol, source: Acros) and the mixture was stirred at room temperature for 1 hour. Toluene (70 mL) was then added and the reaction mixture was heated to reflux overnight. Upon completion of the reaction, it was cooled to room temperature, and the organic layer was separated and discarded. The aqueous layer was neutralized with 10% sodium hydroxide solution (350 mL) and subsequently extracted with dichloromethane (2 x 100 mL). The organic phases were combined, washed sequentially with water (2 x 100 mL) and saturated aqueous sodium chloride solution (2 x 100 mL), dried over anhydrous sodium sulfate, and concentrated under reduced pressure. Purification by silica gel column chromatography (eluent: ethyl acetate) afforded N,N,2-trimethylquinolin-6-amine 8.44 g (62% yield) as brown solid.1H NMR (500 MHz): δ 7.87 (d, J = 9.3 Hz, 1H), 7.83 (d, J = 8.3 Hz, 1H), 7.31 (dd, J = 9.3, 2.9 Hz, 1H), 7.13 (dd, J = 9.3, 2.9 Hz, 1H), 7.13 (dd, J = 9.3, 2.9 Hz, 1H). 1H), 7.13 (d, J = 8.3 Hz, 1H), 6.76 (d, J = 2.9 Hz, 1H), 3.01 (s, 6H), 2.66 (s, 3H). 13C NMR (125.8 MHz): δ 154.54, 148.12, 141.89, 134.43, 129.10, 127.77, 122.11, 119.30, 105.41, 40.78, 24.92.
References
[1] Organic Letters, 2012, vol. 14, # 24, p. 6366 - 6369
[2] Patent: WO2014/187874, 2014, A1. Location in patent: Page/Page column 25
[3] Patent: CN105018072, 2017, B. Location in patent: Paragraph 0021; 0030; 0031
[4] Patent: CN105001160, 2017, B. Location in patent: Paragraph 0025; 0026; 0027
N,N,2-trimethylquinolin-6-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N,N,2-trimethylquinolin-6-amine manufacturers
- Product
- N,N,2-Trimethylquinolin-6-amine 92-99-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.6%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- N,N,2-trimethylquinolin-6-amine 92-99-9
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-21
- Product
- N,N,2-trimethylquinolin-6-amine 92-99-9
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-21