2-amino-3-chlorophenol
- Product Name
- 2-amino-3-chlorophenol
- CAS No.
- 56962-00-6
- Chemical Name
- 2-amino-3-chlorophenol
- Synonyms
- 2-amino-3-chlorophenol;Phenol,2-aMino-3-chloro-;2-Hydroxy-6-chloroaniline
- CBNumber
- CB2945769
- Molecular Formula
- C6H6ClNO
- Formula Weight
- 143.57
- MOL File
- Mol file
2-amino-3-chlorophenol Property
- Melting point:
- 122 °C
- Boiling point:
- 242.6±25.0 °C(Predicted)
- Density
- 1.406±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 8.79±0.10(Predicted)
- Appearance
- Light brown to brown Solid
Safety
- HS Code
- 2922290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A617705
- Product name
- 2-Amino-3-chlorophenol
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A617705
- Product name
- 2-Amino-3-chlorophenol
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA154068
- Product name
- 2-Amino-3-chlorophenol
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FA154068
- Product name
- 2-Amino-3-chlorophenol
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 4656-5-54
- Product name
- 2-Amino-3-chlorophenol
- Packaging
- 250mg
- Price
- $124
- Updated
- 2021/12/16
2-amino-3-chlorophenol Chemical Properties,Usage,Production
Uses
2-Amino-3-chlorophenol is a useful research chemical for organic synthesis and other chemical processes. 2-Amino-3-chlorophenol is a useful in the synthesis of Arenoazolylamines as antibiotic compounds
Synthesis
17802-02-7
56962-00-6
General procedure for the synthesis of 2-amino-3-chlorophenol from 2-nitro-3-chlorophenol: 3-chloro-2-nitrophenol (2.5 g, 14.5 mmol) was dissolved in ethanol (30 mL) at room temperature, followed by the addition of tin chloride dihydrate (SnCl2-2H2O, 13 g, 57.8 mmol). The reaction mixture was heated to 90°C and stirred continuously for 2 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the completion of the reaction, the reaction mixture was cooled to room temperature and concentrated under reduced pressure. Ice water (50 mL) was added to the concentrated residue and the pH was adjusted with ammonia solution to 7. Subsequently, extraction was performed with ethyl acetate (3 x 50 mL). The organic layers were combined, washed with saturated saline (50 mL), dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. The residue obtained was ground with hexane (25 mL) to give 2-amino-3-chlorophenol as an off-white solid. Yield: 1.8 g (80% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6) and mass spectrometry (ESI+): 1H NMR δ 9.58 (broad single peak, 1H), 6.69 (double peaks, J = 8.0 Hz, 1H), 6.63 (double peaks, J = 8.0 Hz, 1H), 6.38-6.48 (multiple peaks, 1H), 4.05 (broad single peaks, 2H); mass spectra ( ESI+) m/z 144.09 [M + H]+.
References
[1] Patent: WO2018/37223, 2018, A1. Location in patent: Page/Page column 154; 155
[2] Patent: WO2009/62285, 2009, A1. Location in patent: Page/Page column 64-65
[3] Patent: WO2009/62308, 2009, A1. Location in patent: Page/Page column 73; 74
[4] Patent: WO2009/62288, 2009, A1. Location in patent: Page/Page column 70-71
[5] Patent: WO2009/62289, 2009, A1. Location in patent: Page/Page column 77; 78
2-amino-3-chlorophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-amino-3-chlorophenol manufacturers
- Product
- 2-amino-3-chlorophenol 56962-00-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 2-amino-3-chlorophenol 56962-00-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 2-amino-3-chlorophenol 56962-00-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97-99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-19