3-Bromopyridine-4-carboxamide

Product Name: 3-Bromopyridine-4-carboxamide
CAS No.: 13958-99-1
Chemical Name: 3-Bromopyridine-4-carboxamide
Synonyms: Hybutimibe Impurity 7;9H-CARBAZOL-4-AMIN...;3-Bromoisonicotinamide;Isonicotinamide, 3-bromo-;3-Bromopyridin-4-carboxamide;3-Bromopyridine-4-carboxamide;3-Bromo-4-pyridinecarboxamide;4-Pyridinecarboxamide, 3-bromo-;3-broMo-2-carbaMoylpyridine-4-carboxylic acid;3-Bromopyridine-4-carboxamide ISO 9001：2015 REACH
CBNumber: CB2967411
Molecular Formula: C6H5BrN2O
Formula Weight: 201.02
MOL File: 13958-99-1.mol

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3-Bromopyridine-4-carboxamide Property

Boiling point:: 316.3±27.0 °C(Predicted)
Density: 1.710±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: Sealed in dry,Room Temperature
pka: 14.33±0.50(Predicted)
Appearance: Light brown to brown Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B687903
Product name: 3-Bromoisonicotinamide
Packaging: 50mg
Price: $55
Updated: 2021/12/16

Matrix Scientific

Product number: 073562
Product name: 3-Bromoisonicotinamide
Purity: 95+%
Packaging: 250mg
Price: $54
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB144231
Product name: 3-Bromoisonicotinamide
Packaging: 250mg
Price: $70
Updated: 2021/12/16

AK Scientific

Product number: W3053
Product name: 3-Bromoisonicotinamide
Packaging: 250mg
Price: $122
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB144231
Product name: 3-Bromoisonicotinamide
Packaging: 500mg
Price: $125
Updated: 2021/12/16

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3-Bromopyridine-4-carboxamide Chemical Properties,Usage,Production

Synthesis

541-41-3

13959-02-9

13959-01-8

13958-99-1

General procedure for the synthesis of ethyl 3-bromoisonicotinate and 3-bromopyridine-4-amide from ethyl chloroformate and 3-bromoisonicotinic acid: ethyl chloroformate (0.58 g, 5.4 mmol) was added dropwise to a cooled mixture of 3-bromoisonicotinic acid (1.00 g, 4.6 mmol), anhydrous THF (15 mL) and anhydrous triethylamine (1.0 mL). The mixture was stirred at 0°C for 1 hour and then ammonia was bubbled through the suspension for 15 minutes. The mixture was filtered and the solids were washed with hot acetone. The solvent was evaporated from the combined filtrate and washings and recrystallized from ethanol to give 3-bromopyridine-4-amide (777 mg, 78%) as an off-white powder: melting point 149-150°C; 1H NMR (CDCl3) δ 7.48 (1H, d, J = 4.8 Hz, 5-H), 7.88 (1H, br, NH), 8.11 (1H, br, NH) , 8.65 (1H, d, J = 4.8 Hz, 6-H), 8.84 (1H, s, 2-H); 13C NMR (CDCl3) δ 116.82 (3-C), 122.73 (5-C), 146.02 (4-C), 148.58 (6-C), 151.68 (2-C), 167.03 (C=O); MS m/z 224.9469 (M + Na)+ (C6H581BrN2NaO requires 224.9457), 222.9485 (M + Na)+ (C6H58FBrN2NaO, requires 222.9477). Evaporation of the solvent from the mother liquor gave ethyl 3-bromoisonicotinate (60 mg, 5%) as a yellow liquid: 1H NMR (CDCl3) δ 1.41 (3H, t, J = 7.2 Hz, Me), 4.43 (2H, q, J = 7.3 Hz, CH2), 7.59 (1H, d, J = 4.9 Hz, 5-H), 8.59 (1H, d, J = 4.9 Hz, 6-H), 8.83 (1H, s, 2-H); 13C NMR (CDCl3) δ 14.04 (Me), 62.33 (CH2), 118.71 (3-C), 124.15 (5-C), 139.34 (4-C), 148.41 (6-C), 153.64 (2-C), 164.47 (C = O); MS m/z 253.9623 (M + Na) + (C8H88AlBaNaO2 requires 253.9611), 251.9638 (M + Na) + (C8H89BrNNaO2 requires 251.9631), 224.9469 (M + H) + (C6H581BrN2O requires 224.9457), and 222.9485 (M + H) + (C6H579BrN2O requires 222.9477).

References

[1] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 13, p. 3013 - 3032

3-Bromopyridine-4-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Bromopyridine-4-carboxamide Suppliers

China 59 Germany 2 India 2 United Kingdom 2 United States 7 Global 72

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View Lastest Price from 3-Bromopyridine-4-carboxamide manufacturers

Dideu Industries Group Limited

Product: 3-Bromopyridine-4-carboxamide 13958-99-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-23

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Bromopyridine-4-carboxamide 13958-99-1
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-12

Career Henan Chemical Co

Product: 3-Bromopyridine-4-carboxamide 13958-99-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-07-10

13958-99-1, 3-Bromopyridine-4-carboxamideRelated Search:

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