ChemicalBook > CAS DataBase List > 4-Bromo-5-chloro-2-methylaniline

4-Bromo-5-chloro-2-methylaniline

Product Name
4-Bromo-5-chloro-2-methylaniline
CAS No.
30273-47-3
Chemical Name
4-Bromo-5-chloro-2-methylaniline
Synonyms
4-BROMO-5-CHLORO-2-METHYLANILINE;(4-bromo-5-chloro-2-methylphenyl)amine;BenzenaMine, 4-broMo-5-chloro-2-Methyl-;product NaMe 4-broMo-5-chloro-2-Methylaniline
CBNumber
CB2971780
Molecular Formula
C7H7BrClN
Formula Weight
220.49
MOL File
30273-47-3.mol
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4-Bromo-5-chloro-2-methylaniline Property

Melting point:
98-101°
Boiling point:
292.0±35.0 °C(Predicted)
Density 
1.619±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
2.69±0.10(Predicted)
Appearance
Light brown to brown Solid
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2921490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B695200
Product name
4-Bromo-5-chloro-2-methylaniline
Packaging
100mg
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB74679
Product name
4-Bromo-5-chloro-2-methylaniline
Packaging
250mg
Price
$85
Updated
2021/12/16
Matrix Scientific
Product number
020563
Product name
4-Bromo-5-chloro-2-methylaniline
Purity
98%
Packaging
5g
Price
$14
Updated
2021/12/16
AK Scientific
Product number
W5266
Product name
4-Bromo-5-chloro-2-methylaniline
Packaging
5g
Price
$27
Updated
2021/12/16
Matrix Scientific
Product number
020563
Product name
4-Bromo-5-chloro-2-methylaniline
Purity
98%
Packaging
100g
Price
$132
Updated
2021/12/16
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4-Bromo-5-chloro-2-methylaniline Chemical Properties,Usage,Production

Uses

4-Bromo-5-chloro-2-methylaniline can be used as an intermediate in the manufacturing of dyes and pigments, where its chemical structure imparts color and stability to these products.

Synthesis

95-79-4

30273-47-3

Example 1A; 4-Bromo-5-chloro-2-methylaniline; 321.6 g (2.01 mol) of bromine was slowly added dropwise to 6000 ml of glacial acetic acid solution containing 300.0 g (2.12 mol) of 5-chloro-2-methylaniline at 10-15 °C. After the dropwise addition, the reaction mixture was stirred at room temperature overnight. After completion of the reaction, the precipitate was separated by filtration and the filtrate was washed with ethyl acetate. Subsequently, the resulting solid was stirred with ethyl acetate and saturated sodium bicarbonate solution to separate the organic phase and the solvent was thoroughly removed using a rotary evaporator. After two recrystallizations from hexane, 186 g (38% yield) of the target product 4-bromo-5-chloro-2-methylaniline was obtained.The results of the LC-MS (Method 1) analysis were: retention time Rt = 2.26 min, and mass-to-charge ratio m/z = 220 ([M + H]+).

References

[1] Patent: US2010/105673, 2010, A1. Location in patent: Page/Page column 12

4-Bromo-5-chloro-2-methylaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Bromo-5-chloro-2-methylaniline manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-Bromo-5-chloro-2-methylaniline 30273-47-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-25
Career Henan Chemical Co
Product
4-Bromo-5-chloro-2-methylaniline 30273-47-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kg
Release date
2018-12-25
Hebei Jimi Trading Co., Ltd.
Product
4-Bromo-5-chloro-2-methylaniline 30273-47-3
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500KG
Release date
2019-04-16