MRTX-1719

Product Name: MRTX-1719
CAS No.: 2630904-45-7
Chemical Name: MRTX-1719
Synonyms: MRTX-1719,CRC,Histone Methyltransferase,NSCLC,Inhibitor,MTA,MRTX1719,MRTX 1719,inhibit,PRMT5;2-[4-[4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl]-1-methyl-5-pyrazolyl]-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile;(2R)-2-(4-(4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile;Benzonitrile, 2-[4-[4-(aminomethyl)-1,2-dihydro-1-oxo-6-phthalazinyl]-1-methyl-1H-pyrazol-5-yl]-4-chloro-6-(cyclopropyloxy)-3-fluoro-, (2R)-
CBNumber: CB29782000
Molecular Formula: C23H18ClFN6O2
Formula Weight: 464.89
MOL File: 2630904-45-7.mol

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MRTX-1719 Property

Density: 1.58±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 11.37±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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MRTX-1719 Chemical Properties,Usage,Production

Biological Activity

MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAPDEL SDMA cells[1].

References

[1]. Targeting the genetic and immunological drivers of cancer.

MRTX-1719 Preparation Products And Raw materials

Raw materials

Preparation Products

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MRTX-1719 Suppliers

China 29 United States 1 Global 30

Chengdu DingDang Pharmaceutical Co., Ltd.

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DC Chemicals

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View Lastest Price from MRTX-1719 manufacturers

Henan Fengda Chemical Co., Ltd

Product: MRTX-1719 2630904-45-7
Price: US $8.00-2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-24

2630904-45-7, MRTX-1719Related Search:

MRTX-849 MRTX0902 MRTX1133 INDEX NAME NOT YET ASSIGNED MRTX-EX185

Benzonitrile, 2-[4-[4-(aminomethyl)-1,2-dihydro-1-oxo-6-phthalazinyl]-1-methyl-1H-pyrazol-5-yl]-4-chloro-6-(cyclopropyloxy)-3-fluoro-, (2R)-

MRTX-1719,CRC,Histone Methyltransferase,NSCLC,Inhibitor,MTA,MRTX1719,MRTX 1719,inhibit,PRMT5

2-[4-[4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl]-1-methyl-5-pyrazolyl]-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile

(2R)-2-(4-(4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile

2630904-45-7

C23H18ClFN6O2