ChemicalBook > CAS DataBase List > MRTX-1719

MRTX-1719

Product Name
MRTX-1719
CAS No.
2630904-45-7
Chemical Name
MRTX-1719
Synonyms
MRTX-1719,CRC,Histone Methyltransferase,NSCLC,Inhibitor,MTA,MRTX1719,MRTX 1719,inhibit,PRMT5;2-[4-[4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl]-1-methyl-5-pyrazolyl]-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile;(2R)-2-(4-(4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile;Benzonitrile, 2-[4-[4-(aminomethyl)-1,2-dihydro-1-oxo-6-phthalazinyl]-1-methyl-1H-pyrazol-5-yl]-4-chloro-6-(cyclopropyloxy)-3-fluoro-, (2R)-
CBNumber
CB29782000
Molecular Formula
C23H18ClFN6O2
Formula Weight
464.89
MOL File
2630904-45-7.mol
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MRTX-1719 Property

Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
form 
Solid
pka
11.37±0.40(Predicted)
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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MRTX-1719 Chemical Properties,Usage,Production

Biological Activity

MRTX-1719 is a potent first-in-class selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAPDEL SDMA cells[1].

References

[1]. Targeting the genetic and immunological drivers of cancer.

MRTX-1719 Preparation Products And Raw materials

Raw materials

Preparation Products

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MRTX-1719 Suppliers

Chengdu DingDang Pharmaceutical Co., Ltd.
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028-86040038 13980902949;
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028-85149890
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market@dingdangchem.com
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China
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Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd.
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13771642864
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1078336263
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snhuyu_2008@126.com
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China
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Chengdu Junepharma Technology Co., Ltd
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19938173342 19181793067
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1486288711@qq.com
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China
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167
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Suzhou Chenrui Biotechnology Co. LTD
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17625585511
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qq:1580084073
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1580084073@qq.com
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China
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673
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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15000803246 18149758185
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sales-cpd@caerulumpharma.com
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China
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330
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Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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sales@meilune.com
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China
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4727
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185 18149758185
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sales-cpd@caerulumpharma.com
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China
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Shanghai Lollane Biological Technology Co.,Ltd.
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021-52996696,15000506266 15000506266
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+86-21-52996696
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China
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ShangHai Biochempartner Co.,Ltd
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17754423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
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China
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Shanghai Chaolan Chemical Technology Center
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021-QQ:65489617 15618227136
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21-5161 9052
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Sales@ATKchemical.com
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China
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DC Chemicals
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021-58447131 13564518121
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sales@dcchemicals.com
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ShangHai ChuanQian Chemcial Technique Centre
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15869524721
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3525679403@qq.com
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Chunchuang (Wuhan) Technology Co., Ltd
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15342225168
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yutianchun2007@126.com
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Nantong Hi-Future Biotechnology Co., Ltd
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18051384581
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sales@chemhifuture.com
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Bide Pharmatech Ltd.
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400-1647117 13681763483
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product02@bidepharm.com
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China
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Changzhou Bojia Biomedical Technology Co., Ltd.
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2122619822
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czbjpharma@126.com
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China
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Changzhou Borl Biotechnology Co.,LTD
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13606124132;13656121842
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luyan0021@163.com
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China
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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Shanghai Tachizaki Biomedical Research Center
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18014399201
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sales@chemlab-tachizaki.com
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Suzhou Haiben Pharmaceutical Co., Ltd
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14760821013 13564957716
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1816280386@qq.com
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China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66113011 18112977050
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cb5@aikonchem.com
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China
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https://hanhongsci.com/
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021-54306202 18917919676
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
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Wuhan WinYuanBei Trading Company
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China
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Shanghai jerryxing Biomedical Technology Co., Ltd
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17721492509
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Jinan Junnuo Trading Co., LTD
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13345898948
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RD International Technology Co., Limited
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18024082417
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market@ubiochem.com
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ATK CHEMICAL COMPANY LIMITED
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+undefined-21-51877795
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+86 21 5161 9052/ 5187 7796
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ivan@atkchemical.com
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SHANGHAI KEAN TECHNOLOGY CO., LTD.
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+8613817748580
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021-50175322
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Henan Fengda Chemical Co., Ltd
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+86-371-86557731 +86-13613820652
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86-0371-86557731
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info@fdachem.com
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Chemtour Biotech Co., Ltd
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+8617327281506
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Nantong HI-FUTURE Biology Co., Ltd.
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+undefined18051384581
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sales@chemhifuture.com
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3135
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View Lastest Price from MRTX-1719 manufacturers

Henan Fengda Chemical Co., Ltd
Product
MRTX-1719 2630904-45-7
Price
US $8.00-2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-24

2630904-45-7, MRTX-1719Related Search:


  • Benzonitrile, 2-[4-[4-(aminomethyl)-1,2-dihydro-1-oxo-6-phthalazinyl]-1-methyl-1H-pyrazol-5-yl]-4-chloro-6-(cyclopropyloxy)-3-fluoro-, (2R)-
  • MRTX-1719,CRC,Histone Methyltransferase,NSCLC,Inhibitor,MTA,MRTX1719,MRTX 1719,inhibit,PRMT5
  • 2-[4-[4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl]-1-methyl-5-pyrazolyl]-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile
  • (2R)-2-(4-(4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile
  • 2630904-45-7
  • C23H18ClFN6O2