PYRIDINE-2-CARBOXAMIDINE
- Product Name
- PYRIDINE-2-CARBOXAMIDINE
- CAS No.
- 52313-50-5
- Chemical Name
- PYRIDINE-2-CARBOXAMIDINE
- Synonyms
- Picolinamidine;2-Pyridinecarboxamidine;2-PyridinecarboxiMidaMide
- CBNumber
- CB31011602
- Molecular Formula
- C6H7N3
- Formula Weight
- 121.14
- MOL File
- 52313-50-5.mol
PYRIDINE-2-CARBOXAMIDINE Property
- Boiling point:
- 240.7±32.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 10.68±0.40(Predicted)
- Appearance
- White to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- Z3386
- Product name
- Pyridine-2-carboxamidine
- Packaging
- 10g
- Price
- $821
- Updated
- 2021/12/16
- Product number
- CHM0147151
- Product name
- PYRIDINE-2-CARBOXIMIDAMIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $4966.5
- Updated
- 2021/12/16
- Product number
- 52313505
- Product name
- Picolinimidamide
- Packaging
- 10g
- Price
- $827.19
- Updated
- 2021/12/16
- Product number
- CM178804
- Product name
- picolinimidamide
- Purity
- 95%
- Packaging
- 1g
- Price
- $121
- Updated
- 2021/12/16
- Product number
- SC-41999
- Product name
- PYRIDINE-2-CARBOXAMIDINE
- Purity
- 95%
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
PYRIDINE-2-CARBOXAMIDINE Chemical Properties,Usage,Production
Synthesis Reference(s)
The Journal of Organic Chemistry, 26, p. 412, 1961 DOI: 10.1021/jo01061a034
Synthesis
100-70-9
4039-32-1
52313-50-5
Lithium bis(trimethylsilyl)amide (1M tetrahydrofuran solution, 60.5 mL, 60.5 mmol) was slowly added dropwise to a solution of 2-cyanopyridine (3.0 g, 28.8 mmol) in anhydrous ether (30 mL) at 0 °C. The reaction mixture was kept cooled at 0 °C, followed by the addition of 3M hydrochloric acid (54 mL) with continuous stirring for 30 min. After completion of the reaction, water (135 mL) was added for dilution and the organic phase was separated. The aqueous phase was adjusted to pH 14 with saturated aqueous sodium hydroxide and subsequently extracted with dichloromethane (3 times). The organic extracts were combined, dried over anhydrous sodium sulfate and concentrated in vacuum to afford pyridine-2-carboxamidine (1.70 g, 49% yield).
References
[1] Patent: US2012/202806, 2012, A1
PYRIDINE-2-CARBOXAMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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