1,4-Bis(N,N'-diethylene phosphamide)piperazine

Product Name: 1,4-Bis(N,N'-diethylene phosphamide)piperazine
CAS No.: 738-99-8
Chemical Name: 1,4-Bis(N,N'-diethylene phosphamide)piperazine
Synonyms: dipin;Dipine;NSC80096;NSC-80096;NSC 80096;1,4-Bis(N,N'-diethylene phosphamide)piperazine;Piperazine, 1,4-bis[bis(1-aziridinyl)phosphinyl]-;1,4-PIPERAZINEDIHYLBIS(BIS(1-AZIRIDINYL)-PHOPHINEOXIDE;1,4-Piperazinediylbis[bis(1-aziridinyl)phosphine oxide];PHOSPHINEOXIDE,1,4-PIPERAZINEDIYLBIS(BIS(1-AZIRIDINYL)-
CBNumber: CB31016667
Molecular Formula: C12H24N6O2P2
Formula Weight: 346.31
MOL File: 738-99-8.mol

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1,4-Bis(N,N'-diethylene phosphamide)piperazine Property

Melting point:: 187°
form: solid
color: Crystals from C6H6

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Safety

Toxicity: LD50 orl-mus: 68 mg/kg RPTOAN 36,240,73

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 058327
Product name: 1,4-Bis[bis(1-aziridinyl)phosphoryl]piperazine
Packaging: 500mg
Price: $132
Updated: 2021/12/16

AK Scientific

Product number: 9035AE
Product name: 1,4-Bis[bis(1-aziridinyl)phosphoryl]piperazine
Packaging: 500mg
Price: $228
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0297008
Product name: DIPIN
Purity: 95.00%
Packaging: 5MG
Price: $503.9
Updated: 2021/12/16

Aronis compounds

Product number: BBC/208
Product name: 1,4-bis[bis(1-aziridinyl)phosphoryl]piperazine
Packaging: 10g
Price: $511
Updated: 2021/12/16

Crysdot

Product number: CD61000309
Product name: Piperazine-1,4-diylbis(di(aziridin-1-yl)phosphineoxide)
Purity: 95+%
Packaging: 5g
Price: $704
Updated: 2021/12/16

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1,4-Bis(N,N'-diethylene phosphamide)piperazine Chemical Properties,Usage,Production

Uses

Antineoplastic agent-1 is an alkylating agent and a genotoxic agent that can induce DNA damage. Antineoplastic agent-1 can lead to irreversible damage and progressive death of liver cells due to necroptosis and apoptosis. Antineoplastic agent-1 can cause alkylation damage to hematopoietic cells and stromal cells in the bone marrow. Antineoplastic agent-1 can be used in tumor research[1][2].

Safety Profile

Poison by ingestion,intraperitoneal, and subcutaneous routes. Humanmutation data reported. When heated to decomposition itemits very toxic fumes of POx and NOx.

References

[1] Factor VM, Radaeva SA, Thorgeirsson SS. Origin and fate of oval cells in dipin-induced hepatocarcinogenesis in the mouse. Am J Pathol. 1994 Aug;145(2):409-22. PMID:8053498
[2] Jensen MR, et al. Regulation of cyclin G1 during murine hepatic regeneration following Dipin-induced DNA damage. Hepatology. 1998 Aug;28(2):537-46. DOI:10.1002/hep.510280235

1,4-Bis(N,N'-diethylene phosphamide)piperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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1,4-Bis(N,N'-diethylene phosphamide)piperazine Suppliers

China 1 Russia 1 United States 3 Global 5

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29357
Advantage: 58

TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19961
Advantage: 58

738-99-8, 1,4-Bis(N,N'-diethylene phosphamide)piperazineRelated Search:

N-bis(dimethylamino)phosphoryl-N-methyl-methanamine phosphoramide 1,4-Bis(N,N'-diethylene phosphamide)piperazine 1-Arizidinyl-bis(dimethylamino)phosphine oxide pentamethylphosphoramide

1,4-Bis(N,N'-diethylene phosphamide)piperazine

dipin

1,4-PIPERAZINEDIHYLBIS(BIS(1-AZIRIDINYL)-PHOPHINEOXIDE

PHOSPHINEOXIDE,1,4-PIPERAZINEDIYLBIS(BIS(1-AZIRIDINYL)-

1,4-Piperazinediylbis[bis(1-aziridinyl)phosphine oxide]

Dipine

Piperazine, 1,4-bis[bis(1-aziridinyl)phosphinyl]-

NSC 80096

NSC80096

NSC-80096

738-99-8

C12H24N6O2P2