Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI)

Product Name: Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI)
CAS No.: 405230-79-7
Chemical Name: Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI)
Synonyms: Pyridine,2-chloro-5-fluoro-, 1-oxide;2-chloro-5-fluoro-1-oxidopyridin-1-ium;Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI)
CBNumber: CB31046909
Molecular Formula: C5H3ClFNO
Formula Weight: 147.53
MOL File: 405230-79-7.mol

More

Less

Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI) Property

Melting point:: 98-100℃
Boiling point:: 311.3±22.0 °C(Predicted)
Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -1.34±0.10(Predicted)

More

Less

Safety

HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: C585785
Product name: 2-Chloro-5-fluoropyridine-N-oxide
Packaging: 500mg
Price: $130
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0363543
Product name: 2-CHLORO-5-FLUOROPYRIDINE-1-OXIDE
Purity: 95.00%
Packaging: 5MG
Price: $500.7
Updated: 2021/12/16

Matrix Scientific

Product number: 085210
Product name: 2-Chloro-5-fluoropyridine 1-oxide
Purity: 97%
Packaging: 1g
Price: $524
Updated: 2021/12/16

AK Scientific

Product number: 5485AB
Product name: 2-Chloro-5-fluoropyridine1-oxide
Packaging: 10g
Price: $652
Updated: 2021/12/16

Ambeed

Product number: A673254
Product name: 2-Chloro-5-fluoropyridine1-oxide
Purity: 97%
Packaging: 25g
Price: $743
Updated: 2021/12/16

More

Less

Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI) Chemical Properties,Usage,Production

Synthesis

31301-51-6

405230-79-7

General procedure: 2-chloro-5-fluoropyridine (20 g, 152 mmol) was dissolved in trifluoroacetic acid (150 mL) under nitrogen protection. Hydrogen peroxide (78 mL, 760 mmol) was slowly added to the solution at 70°C. The reaction mixture was stirred at 70°C for 16 hours. Upon completion of the reaction, the reaction solution was concentrated. Water and dichloromethane (DCM) were added to the residue. The pH was adjusted to 7 with 28% ammonium hydroxide solution and then extracted with DCM. The organic phase was dried with anhydrous magnesium sulfate (MgSO4) and concentrated to give 2-chloro-5-fluoropyridine 1-oxide (20.1 g, 136 mmol, 90% yield), and the product could be used in the next reaction without further purification.LC-MS analysis showed m/z 147.6 (M+H) with retention time of 0.78 min.

References

[1] Patent: WO2016/203401, 2016, A1. Location in patent: Page/Page column 191
[2] Patent: WO2011/113802, 2011, A2. Location in patent: Page/Page column 106
[3] Nucleosides, Nucleotides and Nucleic Acids, 2001, vol. 20, # 12, p. 1975 - 2000
[4] Patent: US2004/116362, 2004, A1. Location in patent: Page/Page column 12; Figure 1
[5] Patent: US2012/95031, 2012, A1. Location in patent: Page/Page column 158-159

Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI) Suppliers

China 34 Europe 1 India 1 United Kingdom 2 United States 1 Global 39

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jinan Trio PharmaTech Co., Ltd.

Tel: 0531-88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com
Country: China
ProdList: 1856
Advantage: 62

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 0512-0512-52358471 17715136450
Fax: 05125235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 12127
Advantage: 58

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9288
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Jinan Kaixi Biotechnology Co., Ltd.

Tel: 13370511208; 15853141736
Fax: -
Email: 461667177@qq.com
Country: China
ProdList: 613
Advantage: 55

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 10410
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Rlavie Technology Co., Ltd.

Tel: 21-67759270 17717059219
Fax: QQ：1479352695
Email: sales@rlavie.com
Country: China
ProdList: 1620
Advantage: 55

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
ProdList: 4877
Advantage: 58

Suzhou Adelaide Chemical Technology Co., Ltd.

Tel: 15995785122
Email: 3003020078@qq.com
Country: China
ProdList: 1198
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Shanghai Botuo Biotechnology Co., LTD

Tel: 16621358918
Fax: QQ:402135374
Email: botuopharma888@163.com
Country: China
ProdList: 9208
Advantage: 58

Henan Lavoisier Chemical Products Co. Ltd

Tel: 0371-63682289 18625781376
Fax: 18625781376
Email: jacschem@163.com
Country: China
ProdList: 4967
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Wuhan Brin Technology Co., Ltd.

Tel: 3456065315 13260619011
Email: 3456065315@qq.com
Country: China
ProdList: 2198
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 15697567703
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 49999
Advantage: 58

Shandong Renyi Biotechnology Co., Ltd

Tel: 1859-6138-997 13306222239
Email: lijingkeji2023@163.com
Country: China
ProdList: 696
Advantage: 58

Yantai Shengkailun Chemical Technology Co., Ltd.

Tel: 13356901049
Email: mark@sklnchem.cn
Country: China
ProdList: 9993
Advantage: 58

Changzhou Yourui Pharmaceutical Technology Co., Ltd

Tel: 18168818882
Email: 877458914@qq.com
Country: China
ProdList: 3183
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 33024
Advantage: 60

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Shanghai Qimin Biotechnology Co., Ltd.

Tel: 13032137268
Email: 171198252@qq.com
Country: China
ProdList: 130
Advantage: 58

More

Less

View Lastest Price from Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI) manufacturers

Career Henan Chemical Co

Product: Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI) 405230-79-7
Price: US $0.01/KG
Min. Order: 1KG
Purity: 98%; 99%
Supply Ability: 500g;1kg； 25kg
Release date: 2020-01-09

405230-79-7, Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI)Related Search:

Pyridine, 2-chloro-5-fluoro-, 1-oxide (9CI)

2-chloro-5-fluoro-1-oxidopyridin-1-ium

Pyridine,2-chloro-5-fluoro-, 1-oxide

405230-79-7

PYRIDINE