Isoquinoline, 5-iodo- (9CI)

Product Name: Isoquinoline, 5-iodo- (9CI)
CAS No.: 58142-99-7
Chemical Name: Isoquinoline, 5-iodo- (9CI)
Synonyms: Isoquinoline, 5-iodo-;DSRM-3716, 10 mM in DMSO;Isoquinoline, 5-iodo- (9CI);DSRM-3716 (Synonyms: 5-Iodoisoquinoline);DSRM3716,SARM1,DSRM-3716,NADase,neurodegenerative,cADPR,Inhibitor,5-Iodoisoquinoline,DSRM 3716,axon,inhibit
CBNumber: CB31053800
Molecular Formula: C9H6IN
Formula Weight: 255.06
MOL File: 58142-99-7.mol

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Isoquinoline, 5-iodo- (9CI) Property

Boiling point:: 336.8±15.0 °C(Predicted)
Density: 1.837±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: Ethanol:25.51(Max Conc. mg/mL);100.0(Max Conc. mM)
DMSO:25.51(Max Conc. mg/mL);100.0(Max Conc. mM)
form: solid
pka: 4.48±0.13(Predicted)
color: Yellow to brown

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Safety

HS Code: 2933491090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

AK Scientific

Product number: Y5477
Product name: 5-Iodoisoquinoline
Packaging: 250mg
Price: $49
Updated: 2021/12/16

ChemScene

Product number: CS-0041401
Product name: 5-Iodoisoquinoline
Purity: >97.0%
Packaging: 1g
Price: $93
Updated: 2021/12/16

Apolloscientific

Product number: OR918696
Product name: 5-Iodoisoquinoline
Purity: >98%
Packaging: 1g
Price: $204
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-H-0G
Product name: 5-Iodoisoquinoline
Purity: 98.0%
Packaging: 1g
Price: $327
Updated: 2021/12/16

ChemScene

Product number: CS-0041401
Product name: 5-Iodoisoquinoline
Purity: >97.0%
Packaging: 5g
Price: $360
Updated: 2021/12/16

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Isoquinoline, 5-iodo- (9CI) Chemical Properties,Usage,Production

Biological Activity

DSRM-3716 is a potent and selective SARM1 NADase inhibitor (NAD+ hydrolysis IC50 = 75 nM using recombinant SARM1 SAM-TIR construct) th at recapitulates the SARM1-/- phenotype and protects axons from degeneration induced by axotomy (EC50 = 2.1/1.9 μM by fragmentation/NfL release using mouse DRG neurons; 81/88% protection by 1/3 μM DSRM-3716 using human iPSC-derived motor neurons) or mitochondrial dysfunction (3-30 μM DSRM-3716 against 25 μM rotenone-induced injury; mouse DRG neurons). Mechanistically, DSRM-3716 undergoes base exchange with the nicotinamide (NAM) moiety of nicotinamide adenine dinucleotide (NAD+) to yield the bona fide inhibitor 1AD.

storage

Store at -20°C

Isoquinoline, 5-iodo- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Isoquinoline, 5-iodo- (9CI) Suppliers

China 73 Europe 1 India 2 United States 6 Global 82

Energy Chemical

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View Lastest Price from Isoquinoline, 5-iodo- (9CI) manufacturers

Career Henan Chemica Co

Product: Isoquinoline, 5-iodo- (9CI) 58142-99-7
Price: US $0.01/KG
Min. Order: 1KG
Purity: 95%-99%
Supply Ability: 1kg; 5kg; 10kg
Release date: 2020-10-27

58142-99-7, Isoquinoline, 5-iodo- (9CI)Related Search:

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Isoquinoline, 5-iodo- (9CI)

Isoquinoline, 5-iodo-

DSRM-3716 (Synonyms: 5-Iodoisoquinoline)

DSRM3716,SARM1,DSRM-3716,NADase,neurodegenerative,cADPR,Inhibitor,5-Iodoisoquinoline,DSRM 3716,axon,inhibit

DSRM-3716, 10 mM in DMSO

58142-99-7

ISOQUINOLINE