(S)-2-Amino-2-(3-fluorophenyl)ethanol
- Product Name
- (S)-2-Amino-2-(3-fluorophenyl)ethanol
- CAS No.
- 325152-98-5
- Chemical Name
- (S)-2-Amino-2-(3-fluorophenyl)ethanol
- Synonyms
- (S)-2-AMino-2-(3-fluorophenyl)ethanol;(2S)-2-amino-2-(3-fluorophenyl)ethanol;Benzeneethanol, β-amino-3-fluoro-, (βS)-;(S)-2-amino-2-(3-fluorophenyl)ethan-1-ol;(2S)-2-AMino-2-(3-fluorophenyl)ethan-1-ol;Benzeneethanol, beta-amino-3-fluoro-, (betaS)- (9CI)
- CBNumber
- CB31072708
- Molecular Formula
- C8H10FNO
- Formula Weight
- 155.17
- MOL File
- 325152-98-5.mol
(S)-2-Amino-2-(3-fluorophenyl)ethanol Property
- Melting point:
- 101-103 °C
- Boiling point:
- 286.3±25.0 °C(Predicted)
- Density
- 1.208±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 12.40±0.10(Predicted)
Safety
- HS Code
- 2922190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- PC908892
- Product name
- (S)-2-Amino-2-(3-fluorophenyl)ethanol
- Purity
- 97%
- Packaging
- 250mg
- Price
- $270
- Updated
- 2021/12/16
- Product number
- PC908892
- Product name
- (S)-2-Amino-2-(3-fluorophenyl)ethanol
- Purity
- 97%
- Packaging
- 500mg
- Price
- $405
- Updated
- 2021/12/16
- Product number
- CCH0030547
- Product name
- (2S)-2-AMINO-2-(3-FLUOROPHENYL)ETHAN-1-OL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.16
- Updated
- 2021/12/16
- Product number
- PC908892
- Product name
- (S)-2-Amino-2-(3-fluorophenyl)ethanol
- Purity
- 97%
- Packaging
- 1g
- Price
- $600
- Updated
- 2021/12/16
- Product number
- 325152985
- Product name
- (S)-2-Amino-2-(3-fluorophenyl)ethanol
- Packaging
- 1g
- Price
- $535.6
- Updated
- 2021/12/16
(S)-2-Amino-2-(3-fluorophenyl)ethanol Chemical Properties,Usage,Production
Uses
Used as an intermediate in laboratory research.
Preparation
(Rs,2S)-N-((tert-butyldimethylsilyloxy)-1-(4-fluorophenyl)ethyl)-2-methylpropane-2-sulfinamide (0.280 g, 0.749 mmol) was dissolved in MeOH (10 mL) and then HCl/MeOH (4 M, 2.0 mL) was added. The solution was stirred at room temperature for 3 h. After that, the solvent was removed under vacuum and the residue neutralized with saturated NaHCO3 (20 mL). The mixture was extracted with CH2Cl2/MeOH and the organic phases dried (Na2SO4) and concentrated to obtained (S)-2-Amino-2-(3-fluorophenyl)ethanol.
Reactions
By coupling an amine group to a carboxyl group, (S)-2-Amino-2-(3-fluorophenyl)ethanol could be employed to synthesize (S)-N-{1-(3-fluorophenyl)-2-hydroxyethyl}-4-{5-methyl-2-(phenylamino)pyrimidin-4-yl}-1H-pyrrole-2-carboxamide..
Synthesis
(S)-2-Amino-2-(3-fluorophenyl)ethanol can be prepared by the amination reaction of 1-Ethenyl-3-fluorobenzene and ammonia water.
(S)-2-Amino-2-(3-fluorophenyl)ethanol Preparation Products And Raw materials
Raw materials
Preparation Products
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