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(S)-2-Amino-2-(3-fluorophenyl)ethanol

Product Name
(S)-2-Amino-2-(3-fluorophenyl)ethanol
CAS No.
325152-98-5
Chemical Name
(S)-2-Amino-2-(3-fluorophenyl)ethanol
Synonyms
(S)-2-AMino-2-(3-fluorophenyl)ethanol;(2S)-2-amino-2-(3-fluorophenyl)ethanol;Benzeneethanol, β-amino-3-fluoro-, (βS)-;(S)-2-amino-2-(3-fluorophenyl)ethan-1-ol;(2S)-2-AMino-2-(3-fluorophenyl)ethan-1-ol;Benzeneethanol, beta-amino-3-fluoro-, (betaS)- (9CI)
CBNumber
CB31072708
Molecular Formula
C8H10FNO
Formula Weight
155.17
MOL File
325152-98-5.mol
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(S)-2-Amino-2-(3-fluorophenyl)ethanol Property

Melting point:
101-103 °C
Boiling point:
286.3±25.0 °C(Predicted)
Density 
1.208±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
12.40±0.10(Predicted)
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Safety

HS Code 
2922190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Apolloscientific
Product number
PC908892
Product name
(S)-2-Amino-2-(3-fluorophenyl)ethanol
Purity
97%
Packaging
250mg
Price
$270
Updated
2021/12/16
Apolloscientific
Product number
PC908892
Product name
(S)-2-Amino-2-(3-fluorophenyl)ethanol
Purity
97%
Packaging
500mg
Price
$405
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0030547
Product name
(2S)-2-AMINO-2-(3-FLUOROPHENYL)ETHAN-1-OL
Purity
95.00%
Packaging
5MG
Price
$503.16
Updated
2021/12/16
Apolloscientific
Product number
PC908892
Product name
(S)-2-Amino-2-(3-fluorophenyl)ethanol
Purity
97%
Packaging
1g
Price
$600
Updated
2021/12/16
Alichem
Product number
325152985
Product name
(S)-2-Amino-2-(3-fluorophenyl)ethanol
Packaging
1g
Price
$535.6
Updated
2021/12/16
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(S)-2-Amino-2-(3-fluorophenyl)ethanol Chemical Properties,Usage,Production

Uses

Used as an intermediate in laboratory research.

Preparation

(Rs,2S)-N-((tert-butyldimethylsilyloxy)-1-(4-fluorophenyl)ethyl)-2-methylpropane-2-sulfinamide (0.280 g, 0.749 mmol) was dissolved in MeOH (10 mL) and then HCl/MeOH (4 M, 2.0 mL) was added. The solution was stirred at room temperature for 3 h. After that, the solvent was removed under vacuum and the residue neutralized with saturated NaHCO3 (20 mL). The mixture was extracted with CH2Cl2/MeOH and the organic phases dried (Na2SO4) and concentrated to obtained (S)-2-Amino-2-(3-fluorophenyl)ethanol.

Reactions

By coupling an amine group to a carboxyl group, (S)-2-Amino-2-(3-fluorophenyl)ethanol could be employed to synthesize (S)-N-{1-(3-fluorophenyl)-2-hydroxyethyl}-4-{5-methyl-2-(phenylamino)pyrimidin-4-yl}-1H-pyrrole-2-carboxamide..

Synthesis

(S)-2-Amino-2-(3-fluorophenyl)ethanol can be prepared by the amination reaction of 1-Ethenyl-3-fluorobenzene and ammonia water.

(S)-2-Amino-2-(3-fluorophenyl)ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-2-Amino-2-(3-fluorophenyl)ethanol Suppliers

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325152-98-5, (S)-2-Amino-2-(3-fluorophenyl)ethanolRelated Search:

Ethanol

  • (2S)-2-AMino-2-(3-fluorophenyl)ethan-1-ol
  • (S)-2-AMino-2-(3-fluorophenyl)ethanol
  • Benzeneethanol, beta-amino-3-fluoro-, (betaS)- (9CI)
  • (S)-2-amino-2-(3-fluorophenyl)ethan-1-ol
  • (2S)-2-amino-2-(3-fluorophenyl)ethanol
  • Benzeneethanol, β-amino-3-fluoro-, (βS)-
  • 325152-98-5
  • HALIDE