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5-Fluorobarbituric acid

Product Name
5-Fluorobarbituric acid
CAS No.
767-80-6
Chemical Name
5-Fluorobarbituric acid
Synonyms
5-Fluorobarbituric acid;5-FluoropyriMidine-2,4,6-triol;5-Fluoropyrimidine-2,4,6(1H,3H,5H)-trione;2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-fluoro-;5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione;2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-fluoro- (9CI);2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-fluoro- (9CI) ISO 9001:2015 REACH
CBNumber
CB31081168
Molecular Formula
C4H3FN2O3
Formula Weight
146.08
MOL File
767-80-6.mol
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5-Fluorobarbituric acid Property

Melting point:
260℃ (dec.) (acetic acid )
Density 
1.63±0.1 g/cm3 (20 ºC 760 Torr)
pka
2.17±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0367466
Product name
5-FLUOROPYRIMIDINE-2,4,6-TRIOL
Purity
95.00%
Packaging
1G
Price
$294
Updated
2021/12/16
AK Scientific
Product number
1965AC
Product name
5-Fluoropyrimidine-2,4,6-triol
Packaging
5g
Price
$1072
Updated
2021/12/16
Crysdot
Product number
CD11059984
Product name
5-Fluoropyrimidine-2,4,6-triol
Purity
96%
Packaging
1g
Price
$119
Updated
2021/12/16
Chemenu
Product number
CM121164
Product name
5-Fluoropyrimidine-2,4,6-triol
Purity
96%
Packaging
1g
Price
$122
Updated
2021/12/16
Chemenu
Product number
CM121164
Product name
5-Fluoropyrimidine-2,4,6-triol
Purity
96%
Packaging
5g
Price
$337
Updated
2021/12/16
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5-Fluorobarbituric acid Chemical Properties,Usage,Production

Preparation

synthesis of 5-Fluorobarbituric acid: Urea (1.50 g, 25 mmol) was added to the solution of sodium (1.2 g, 53 mmol) in anhydrous ethanol (50 mL) and the mixture was heated to reflux. Diethyl 2-fluoromalonate (4.45 g, 25 mmol) was added dropwise over 10 minutes and the mixture was heated at reflux for 1h. After cooling to room temperature, the solution was filtered, the residue was washed with ethanol (20 mL), dissolved in water (30 mL) and acidified with HCl to pH 1. The precipitated product was recrystallized from the liquor to afford 5-fluorobarbituric acid (1.87 g, 51%) as a tan powder.
m.p.: >300 °C; ([M + H]+ , 147.0206, C4H4FN2O3 requires: [M]+ , 147.0204); IR (neat,cm-1 ) 2926, 2828, 1578, 1383, 1241, 1128; δF (D2O + NaOD, 376 MHz): -191.95 (s); δC (D2O + NaOD, 100 MHz) 131.89 (d, 1 JCF 214.4, C-F), 157.77 (d, 4 JCF 6.2, C-NH), 164.59 (d, 2 JCF 13.4, CvO); m/z (ASAP) 147 (25%, [M + H]+ ).18a

5-Fluorobarbituric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Fluorobarbituric acid Suppliers

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View Lastest Price from 5-Fluorobarbituric acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-fluoro- (9CI) 767-80-6
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-26

767-80-6, 5-Fluorobarbituric acidRelated Search:


  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-fluoro- (9CI)
  • 5-FluoropyriMidine-2,4,6-triol
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-fluoro-
  • 5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione
  • 5-Fluorobarbituric acid
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-fluoro- (9CI) ISO 9001:2015 REACH
  • 5-Fluoropyrimidine-2,4,6(1H,3H,5H)-trione
  • 767-80-6
  • C4H3FN2O3
  • PYRIMIDINE