Nepicastat

Product Name: Nepicastat
CAS No.: 173997-05-2
Chemical Name: Nepicastat
Synonyms: SYN117;CS-853;Nepitat;Nepicastat;RS-25560-197;Nepicastat HCl;Nepicastat [inn];Nepicastat (SYN 117);Nepicastat (free base) (SYN-117);SYN117;RS-25560-197;SYN-117;SYN 117
CBNumber: CB31116989
Molecular Formula: C14H15F2N3S
Formula Weight: 295.35
MOL File: 173997-05-2.mol

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Nepicastat Property

Boiling point:: 401.8±55.0 °C(Predicted)
Density: 1.40
storage temp.: Store at -20°C
solubility: DMSO: ≥ 48 mg/mL (162.52 mM)
form: Powder
pka: 11.69±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 474143
Product name: Nepicastat
Packaging: 100mg
Price: $1890
Updated: 2021/12/16

Matrix Scientific

Product number: 093133
Product name: (S)-5-(Aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-1H-imidazole-2(3H)-thione
Purity: 95+%
Packaging: 250mg
Price: $5670
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000869
Product name: NEPICASTAT
Purity: 95.00%
Packaging: 250MG
Price: $8610
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000869
Product name: NEPICASTAT
Purity: 95.00%
Packaging: 1G
Price: $9435.2
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000869
Product name: NEPICASTAT
Purity: 95.00%
Packaging: 10MG
Price: $1006.58
Updated: 2021/12/16

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Nepicastat Chemical Properties,Usage,Production

Uses

Treatment of congestive heart failure (dopamine β-hydroxylase inhibitor).

Definition

ChEBI: Nepicastat is a member of the class of 1,3-dihydroimidazole-2-thiones that is 1,3-dihydro-2H-imidazole-2-thione in which one of the nitrogens is substituted by a 5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl group while the carbon adjacent to it is substituted by an aminomethyl group (the S enantiomer). It is a potent and selective inhibitor of both bovine and human dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. It has a role as an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor. It is a member of tetralins, an organofluorine compound, a primary amino compound and a member of 1,3-dihydroimidazole-2-thiones.

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DBH

Nepicastat Preparation Products And Raw materials

Raw materials

Preparation Products

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Nepicastat Suppliers

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View Lastest Price from Nepicastat manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Nepicastat 173997-05-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Nepicastat 173997-05-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: Nepicastat 173997-05-2
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

173997-05-2, NepicastatRelated Search:

Nepicastat

Nepicastat [inn]

5-(AMinoMethyl)-1-((S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthyl)-4-iMidazoline-2-thione

5-(Aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione

RS-25560-197

SYN117

Nepicastat (free base) (SYN-117)

Nepicastat HCl

(S)-5-(Aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-1H-imidazole-2(3H)-thione

(S)-5-Aminomethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-2,3-dihydro-2-thioxo-1H-imidazole Hydrochloride

(S)-5-(Aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-1H-imidazole-2(3H)-thi

Nepitat

SYN117;RS-25560-197;SYN-117;SYN 117

CS-853

Nepicastat (SYN 117)

2H-Imidazole-2-thione, 5-(aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-

173997-05-2

C14H15F2N3S

API