Droprenilamine
- Product Name
- Droprenilamine
- CAS No.
- 57653-27-7
- Chemical Name
- Droprenilamine
- Synonyms
- Valcor;MG-8926;Droprenilamine;droprenylamine;Droprenilamine USP/EP/BP;N-(3,3-Diphenylpropyl)-α-methylcyclohexaneethanamine;Benzenepropanamine, N-(2-cyclohexyl-1-methylethyl)-γ-phenyl-
- CBNumber
- CB31117340
- Molecular Formula
- C24H33N
- Formula Weight
- 335.532
- MOL File
- 57653-27-7.mol
Droprenilamine Property
- Boiling point:
- 466.0±34.0 °C(Predicted)
- Density
- 0.975±0.06 g/cm3(Predicted)
- pka
- 10.52±0.29(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- API0011284
- Product name
- DROPRENILAMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.38
- Updated
- 2021/12/16
Droprenilamine Chemical Properties,Usage,Production
Originator
Valcor,Maggioni,Italy,1979
Uses
Vasodilator (coronary).
Definition
ChEBI: Droprenilamine is a diarylmethane.
Manufacturing Process
The flask of a Parr hydrogenation apparatus was charged with 10.5 g of 3,3-diphenylpropylamine, 7.7 g of cyclohexylacetone, 50 ml methanol and 150 mg of platinum dioxide. Hydrogen at a pressure of 3 atmospheres was introduced and the mixture stirred. Upon absorption of the theoretical amount of hydrogen, stirring is discontinued, the catalyst is filtered off and the solution is evaporated to dryness. The residue is taken up with ether and the hydrochloride is precipitated with HCl in alcoholic solution. The product, as collected on a filter and washed with ether, is recrystallized from isopropanol. Yield: 17 g (92.5% of theory). MP: 175°C to 177°C.
brand name
Valcor (Maggioni Farmaceutici S.p.A., Italy).
Therapeutic Function
Coronary vasodilator
Droprenilamine Preparation Products And Raw materials
Raw materials
Preparation Products
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