ChemicalBook > CAS DataBase List > 4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)
4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)
- Product Name
- 4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)
- CAS No.
- 73819-26-8
- Chemical Name
- 4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)
- Synonyms
- NSC 305831;NSC 305831-d8;FuraMidine-d8;2,5-Bis(4-guanylphenyl)furan;2,5-bis(4-amidinophenyl)furan;2,5-Bis(4-guanylphenyl)furan-d8;2,5-Bis(4-aMidinophenyl)furan-d8;4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide);Benzenecarboximidamide,4,4'-(2,5-furandiyl)bis-;Benzenecarboximidamide, 4,4'-(2,5-furandiyl)bis-
- CBNumber
- CB31119955
- Molecular Formula
- C18H16N4O
- Formula Weight
- 304.35
- MOL File
- 73819-26-8.mol
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4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide) Chemical Properties,Usage,Production
Uses
Labelled analogue of Furamidine, a diphenylfuran compound belonging to an important class of antimicrobial and antiparasitic agents. Furamidine and its analogues also display antitumor activities and showed antiproliferative activities against various tumor cell lines.
in vivo
Furamidine (1 mg/kg; intraperitoneal injection; 3 times a week and repeated every 4 weeks; for 34 weeks; female NZB/NZW mice) and Irinotecan combined treatment suppresses proteinuria and prolongs survival of lupus-prone NZB/NZW mice. The combination treatment does not change the levels of anti-dsDNA antibodies[3].
| Animal Model: | Female NZB/NZW mice (6-week-old) with Irinotecan (1 mg/kg)[3] |
| Dosage: | 1 mg/kg |
| Administration: | Intraperitoneal injection; 3 times a week and repeated every 4 weeks; for 34 weeks |
| Result: | Suppressed proteinuria and prolongs survival of lupus-prone NZB/NZW mice combined with Irinotecan. |
4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide) Preparation Products And Raw materials
Raw materials
Preparation Products
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73819-26-8, 4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)Related Search:
PAFURAMIDINE
2,5-DIPHENYLFURAN
[4-(2-FURYL)PHENYL]METHYLAMINE
4,4'-(2,5-Furandiyl)bis(benzenecarboximidamide)