a-Hydroxy Tamoxifen

Product Name: a-Hydroxy Tamoxifen
CAS No.: 97151-02-5
Chemical Name: a-Hydroxy Tamoxifen
Synonyms: α-OHTAM;α-OHTAM;α-hydroxy Tamoxifen;(E)-α-Hydroxy tamoxifen;(E)-α-Hydroxy Tamoxifen;(E)-(+/-)-alpha-Hydroxytamoxifen;Benzeneethanol,b-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-a-methyl-,(bE)-;Benzeneethanol, β-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methyl-, (βE)-
CBNumber: CB31176114
Molecular Formula: C26H29NO2
Formula Weight: 387.52
MOL File: 97151-02-5.mol

More

Less

a-Hydroxy Tamoxifen Property

Melting point:: 115-119°C
Boiling point:: 533.8±50.0 °C(Predicted)
Density: 1.094±0.06 g/cm3(Predicted)
storage temp.: Amber Vial, -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 14.13±0.20(Predicted)
form: Solid
color: Pale Yellow to Pale Beige

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 17204
Product name: α-hydroxy Tamoxifen
Purity: ≥98%
Packaging: 500μg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 17204
Product name: α-hydroxy Tamoxifen
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 17204
Product name: α-hydroxy Tamoxifen
Purity: ≥98%
Packaging: 5mg
Price: $214
Updated: 2024/03/01

Cayman Chemical

Product number: 17204
Product name: α-hydroxy Tamoxifen
Purity: ≥98%
Packaging: 10mg
Price: $335
Updated: 2024/03/01

TRC

Product number: H954700
Product name: (E)-α-HydroxyTamoxifen
Packaging: 10mg
Price: $145
Updated: 2021/12/16

More

Less

a-Hydroxy Tamoxifen Chemical Properties,Usage,Production

Description

Tamoxifen is a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. Although it is an antagonist of ER action in breast tissue, it acts as an ER agonist in bone and blood vessels and a partial ER agonist in uterine tissues. α-hydroxy Tamoxifen is a reactive metabolite of tamoxifen that is formed by the action of cytochrome P450 3A4 in human liver. It can be further converted into genotoxic DNA adducts though a mechanism involving reversible O-sulfonation of the hydroxyl moiety, which in rats has been linked with hepatocarcinoma.

Chemical Properties

Pale Yellow Solid

Uses

A metabolite of the chemotherapeutic drug Tamoxifen (T006000). Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation.

Uses

A metabolite of the chemotherapeutic drug tamoxifen. Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation.

Definition

ChEBI: Alpha-Hydroxytamoxifen is a stilbenoid.

a-Hydroxy Tamoxifen Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

a-Hydroxy Tamoxifen Suppliers

Canada 1 China 11 United States 7 Global 19

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14059
Advantage: 65

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6870
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55896
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8141
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 29778
Advantage: 58

97151-02-5, a-Hydroxy TamoxifenRelated Search:

ALPHA-HYDROXYMETOPROLOL Tamoxifen a-Hydroxy Tamoxifen

(E)-α-Hydroxy Tamoxifen

(E)-(+/-)-alpha-Hydroxytamoxifen

α-OHTAM

Benzeneethanol, β-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methyl-, (βE)-

α-hydroxy Tamoxifen

(E)-α-Hydroxy tamoxifen

α-OHTAM

Benzeneethanol,b-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-a-methyl-,(bE)-

97151-02-5

Intermediates & Fine Chemicals

Pharmaceuticals

Amines

Aromatics