ChemicalBook > CAS DataBase List > N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride
- Product Name
- N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride
- CAS No.
- 1177141-67-1
- Chemical Name
- N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride
- Synonyms
- CKI-7 2HCL;CKI-7 dihydrochlorid;CKI-7 Dihydrochloride;CKI-7 (hydrochloride);N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride;N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride;Serum and glucocorticoid-regulated kinase,inhibit,nestin,S6K,Inhibitor,CK1,Casein Kinase,Ribosomal S6 Kinase (RSK),differentiation,SGK,CKI-7,Cyclin dependent kinase,neural,Serum-glucocorticoid regulated kinase,S6K1,MSK1,CDK,CKI 7,Wnt,CKI7,βIII-tubulin,Sox1
- CBNumber
- CB31176497
- Molecular Formula
- C11H14Cl3N3O2S
- Formula Weight
- 358.67176
- MOL File
- 1177141-67-1.mol
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N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Property
- Melting point:
- 187-189°C
- storage temp.
- -20°C
- solubility
- H2O: >5mg/mL
- form
- solid
- color
- white to light tan
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C0742
- Product name
- CKI-7 dihydrochloride
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $211
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C0742
- Product name
- CKI-7 dihydrochloride
- Purity
- ≥98% (HPLC), solid
- Packaging
- 25mg
- Price
- $883
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28268
- Product name
- CKI-7 (hydrochloride)
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28268
- Product name
- CKI-7 (hydrochloride)
- Packaging
- 25mg
- Price
- $533
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28268
- Product name
- CKI-7 (hydrochloride)
- Packaging
- 5mg
- Price
- $161
- Updated
- 2024/03/01
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N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Chemical Properties,Usage,Production
Chemical Properties
Beige Solid
Uses
Found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases
Biochem/physiol Actions
CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.
storage
Store at -20°C
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide Dihydrochloride Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71