Bifluranol
- Product Name
- Bifluranol
- CAS No.
- 34633-34-6
- Chemical Name
- Bifluranol
- Synonyms
- BX-341;Bifluranol;Bifluranolum;Bifluranol(BX341);Phenol, 4,4'-[(1R,2S)-1-ethyl-2-methyl-1,2-ethanediyl]bis[2-fluoro-, rel-
- CBNumber
- CB31178118
- Molecular Formula
- C17H18F2O2
- Formula Weight
- 292.323
- MOL File
- 34633-34-6.mol
Bifluranol Property
- Melting point:
- 158-159°
- Boiling point:
- 361.6±37.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 8.85±0.31(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- API0015950
- Product name
- BIFLURANOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.29
- Updated
- 2021/12/16
- Product number
- CSN21522
- Product name
- Bifluranol
- Packaging
- 10mg
- Price
- $3519
- Updated
- 2021/12/16
Bifluranol Chemical Properties,Usage,Production
Definition
ChEBI: (2S,3R)-bifluranol is a 4,4'-pentane-2,3-diylbis(2-fluorophenol) that has (2S,3R)-stereoconfiguration. It is an enantiomer of a (2R,3S)-bifluranol.
Biological Activity
Bifluranol (BX341) has anti-androgenic activity.
in vivo
The absorption, distribution and excretion of Bifluranol have been studied in mouse, rat, ferret and dog. It is readily absorbed following oral administration, but blood concentrations of Bifluranol are low due to hepatic uptake and biliary excretion. After intravenous administration of [ 3 H]it to rats (200 μg/kg) and ferrets (60 μg/kg) the blood concentrations of 3 H decreases rapidly for the first 2 to 3 h, with the decrease being more rapid in females ( 18 min for rat, 30 min for ferret) than males (1.0 h for rat, 1.4 h for ferret). This is followed by a much slower decline (40 h for rat). , 20 h for ferret) to concentrations at 96 h of less than 15 ng Bifluranol equivalents mL -1 (rat) or 1 ng Bifluranol equivalents mL -1 (ferret).
Bifluranol Preparation Products And Raw materials
Raw materials
Preparation Products
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