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Exiprobenum

Product Name
Exiprobenum
CAS No.
26281-69-6
Chemical Name
Exiprobenum
Synonyms
Exiprobenum;o-[3-(Hexyloxy)-2-hydroxypropoxy]benzoic acid;Benzoic acid, 2-[3-(hexyloxy)-2-hydroxypropoxy]-
CBNumber
CB31178693
Molecular Formula
C16H24O5
Formula Weight
296.36
MOL File
26281-69-6.mol
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Hazard and Precautionary Statements (GHS)

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Exiprobenum Chemical Properties,Usage,Production

Originator

Droctil,Ciba Geigy,Italy,1971

Definition

ChEBI: Exiproben is a member of benzoic acids.

Manufacturing Process

p-Hydroxy-benzoic acid methyl ester was subjected to a condensation reaction with 3-hexoxy-2-hydroxy-1-chloropropane in the presence of sodium ethylate and ethanol as a solvent, yielding p-(3-hexoxy-2-hydroxy)-propoxy-benzoic acid methyl ester.
62 g of this intermediate product were admixed with 250 cc of 2N sodium hydroxide and the resulting mixture was refluxed for three hours. The reaction mixture was allowed to cool and was made acid with concentrated hydrochloric acid while cooling it on ice. An oil separated out which was extracted with ether. The ether extract solution was dried over sodium sulfate and then the ether was distilled off, leaving a crystalline mass as a residue. The crystalline product was recrystallized from a mixture of benzene and petroleum ether, yielding a compound having a MP of 68°C.

Therapeutic Function

Choleretic

Exiprobenum Preparation Products And Raw materials

Raw materials

Preparation Products

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Exiprobenum Suppliers

TargetMol Chemicals Inc.
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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26281-69-6, ExiprobenumRelated Search:


  • Exiprobenum
  • o-[3-(Hexyloxy)-2-hydroxypropoxy]benzoic acid
  • Benzoic acid, 2-[3-(hexyloxy)-2-hydroxypropoxy]-
  • 26281-69-6