ChemicalBook > CAS DataBase List > MK-677

MK-677

Product Name
MK-677
CAS No.
159634-47-6
Chemical Name
MK-677
Synonyms
MK-677;Ibutamoren;Mk677 Sarms;IbutaMoren (MK-677);L 163191;MK-0677;MK-677;IBUTAMOREN (MK-677), CID178024;MK-677?/?Ibutamoren 10mg Tablets;Ibutamoren,MK-677, MK-0677, L-163,191;Ibutamoren mesylate (MK-0667, L163191);(R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide
CBNumber
CB31178916
Molecular Formula
C27H36N4O5S
Formula Weight
528.66
MOL File
159634-47-6.mol
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MK-677 Property

Density 
1.32
pka
15.73±0.46(Predicted)
InChI
InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1
InChIKey
UMUPQWIGCOZEOY-JOCHJYFZSA-N
SMILES
C(N[C@H](COCC1=CC=CC=C1)C(N1CCC2(CC1)C1=C(N(S(C)(=O)=O)C2)C=CC=C1)=O)(=O)C(N)(C)C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0014019
Product name
MK-677 HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$498.05
Updated
2021/12/16
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MK-677 Chemical Properties,Usage,Production

Description

Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191)is a non-peptidic, potent, long acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin.
It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. MK677 has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat.
It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.

Uses

Growth hormone releasing factor.

benefits

The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies. 

Side effects

Side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often, which include:
Increased appetite
Lethargy
Joint pain if you have previous medical conditions or elevated hormone levels
Insulin resistance
Possible increase in prolactin levels. 

Safety

Ibutamoren is a muscle building anabolic compound. It's considered safe if you don't have high blood glucose level and if you don't suffer from congestive heart failure. It's considered a boon for anti aging and it's a life longevity material. It's considered to be more beneficial than to be harmful. The optimal dose for body building is to take 25mg at bedtime for four to six weeks. It is a water retaining compound so beware of bloating.

MK-677 Preparation Products And Raw materials

Raw materials

Preparation Products

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MK-677 Suppliers

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View Lastest Price from MK-677 manufacturers

Shandong Huizhihan Supply Chain Co., Ltd
Product
MK-677/Ibutamoren 159634-47-6
Price
US $0.00-0.00/Bottle
Min. Order
1Bottle
Purity
99%
Supply Ability
2000
Release date
2024-11-11
Shandong Huizhihan Supply Chain Co., Ltd
Product
MK-677/Ibutamoren 10mg Tablets 159634-47-6
Price
US $0.00-0.00/Bottle
Min. Order
1Bottle
Purity
99%
Supply Ability
2000
Release date
2024-11-05
hebei hongtan Biotechnology Co., Ltd
Product
Ibutamoren 159634-47-6
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-05-11

159634-47-6, MK-677Related Search:


  • 2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide
  • IbutaMoren (MK-677)
  • 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide
  • IBUTAMOREN (MK-677), CID178024
  • Ibutamoren,MK-677, MK-0677, L-163,191
  • Ibutamoren
  • L 163191;MK-0677;MK-677
  • (R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide
  • Ibutamoren mesylate (MK-0667, L163191)
  • Propanamide, 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-
  • Mk677 Sarms
  • 159634-47-6 (R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide
  • MK-677
  • MK-677?/?Ibutamoren 10mg Tablets
  • (R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide
  • 159634-47-6
  • C27H36N4O5S