Osanetant
- Product Name
- Osanetant
- CAS No.
- 160492-56-8
- Chemical Name
- Osanetant
- Synonyms
- SR142801;SR-142801;Osanetant;Osanetant >=98% (HPLC);N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide;(R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine;N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide;AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-;Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
- CBNumber
- CB31179397
- Molecular Formula
- C35H41Cl2N3O2
- Formula Weight
- 606.62
- MOL File
- 160492-56-8.mol
Osanetant Property
- Boiling point:
- 727.9±60.0 °C(Predicted)
- Density
- 1.25
- storage temp.
- -20°C
- solubility
- DMSO: soluble15mg/mL, clear
- pka
- 8.33±0.10(Predicted)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D +18 to +24°, c = 1 in methanol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SML0798
- Product name
- Osanetant
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $261
- Updated
- 2024/03/01
- Product number
- SML0798
- Product name
- Osanetant
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $916
- Updated
- 2024/03/01
- Product number
- CS-0003438
- Product name
- Osanetant
- Purity
- >98.0%
- Packaging
- 1mg
- Price
- $260
- Updated
- 2021/12/16
- Product number
- INB0005576
- Product name
- OSANETANT
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $420.1
- Updated
- 2021/12/16
- Product number
- CS-0003438
- Product name
- Osanetant
- Purity
- >98.0%
- Packaging
- 5mg
- Price
- $780
- Updated
- 2021/12/16
Osanetant Chemical Properties,Usage,Production
Biochem/physiol Actions
Osanetant is a selective antagonist of neurokinin 3 receptor NK3. Neurokinins (tachykinins) are members of a family of at least three neuropeptides, substance P, neurokinin A, and neurokinin B (NKB), with each mediating their biological effects through binding to a preferred G-protein-coupled receptor termed NK1, NK2, or NK3, respectively. All three NK receptors are expressed in regions of the central nervous system that are related to emotion and cognition (i.e., amygdala and hippocampus) and have been linked to various degrees in psychiatric disorders. Neurokinin receptors, including NK3 receptors, are also expressed in the motor and sensory systems of the digestive tract. Osanetant was in clinical trials for both irritable bowel syndrome and schizophrenia.
Osanetant Preparation Products And Raw materials
Raw materials
Preparation Products
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