Traxanox
- Product Name
- Traxanox
- CAS No.
- 58712-69-9
- Chemical Name
- Traxanox
- Synonyms
- Traxanox;5H-[1]Benzopyrano[2,3-b]pyridin-5-one, 9-chloro-7-(2H-tetrazol-5-yl)-
- CBNumber
- CB31179973
- Molecular Formula
- C13H6ClN5O2
- Formula Weight
- 299.67
- MOL File
- 58712-69-9.mol
Traxanox Property
- Melting point:
- >300°
N-Bromosuccinimide Price
- Product number
- API0016677
- Product name
- TRAXANOX
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.23
- Updated
- 2021/12/16
Traxanox Chemical Properties,Usage,Production
Uses
Traxanox is an orally available diuretic that enhances phagocytosis of yeast granules by mouse peritoneal macrophages and rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox inhibits IgE-mediated histamine release and cyclic AMP phosphodiesterase activity.Traxanox exhibits anti-inflammatory activity, as it inhibits the anaphylactoid reaction and reduces pleural fluid accumulation in experimental models of inflammation. Traxanox also demonstrates a synergistic effect when combined with hydrocortisone or indomethacin in suppressing adjuvant arthritis in rats.
Definition
ChEBI: Traxanox is a pyridochromene.
References
[1] [Effect of traxanox sodium on inflammatory response] DOI:10.1254/fpj.86.329
[2] Goto K, et al. Inhibitory effect of traxanox sodium on IgE-mediated histamine release from passively-sensitized mast cells of the rat in vitro. Int Arch Allergy Appl Immunol. 1982;68(4):332-337. DOI:10.1159/000233122
[3] Ikegami K, et al. The effects of traxanox sodium of cyclic AMP phosphodiesterase and the concentration of cyclic AMP in the plasma of rats. Chem Pharm Bull (Tokyo). 1983 Feb;31(2):752-5. DOI:10.1248/cpb.31.752
Traxanox Preparation Products And Raw materials
Raw materials
Preparation Products
Traxanox Suppliers
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11973
- Advantage
- 58
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29257
- Advantage
- 58
- Tel
- 400-821-026
- Sales@sangon.com
- Country
- China
- ProdList
- 6710
- Advantage
- 58