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RETREVERSINE

Product Name
RETREVERSINE
CAS No.
1028332-91-3
Chemical Name
RETREVERSINE
Synonyms
RETREVERSINE;2-N-cyclohexyl-6-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine;9H-Purine-2,6-diamine, N2-cyclohexyl-N6-[4-(4-morpholinyl)phenyl]-
CBNumber
CB3118160
Molecular Formula
C21H27N7O
Formula Weight
393.49
MOL File
Mol file
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RETREVERSINE Property

storage temp. 
Store at -20°C
solubility 
DMF: 1.6 mg/ml; DMSO: 2.5 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10006606
Product name
Retreversine
Purity
≥98%
Packaging
500μg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
10006606
Product name
Retreversine
Purity
≥98%
Packaging
1mg
Price
$66
Updated
2024/03/01
Cayman Chemical
Product number
10006606
Product name
Retreversine
Purity
≥98%
Packaging
5mg
Price
$274
Updated
2024/03/01
Cayman Chemical
Product number
10006606
Product name
Retreversine
Purity
≥98%
Packaging
10mg
Price
$477
Updated
2024/03/01
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RETREVERSINE Chemical Properties,Usage,Production

Description

Terminal differentiation of embryonic progenitor cells to form distinct, adult tissues is the hallmark of organogenesis in complex organisms. However, in mammals including humans, this process is not readily reversible. Reversine is a 2,6-disubstituted purine derivative that was identified using a screening system based on the loss of terminal differentiation markers in C2C12 myoblast cells.1 Retreversine is an inactive control molecule, created by simply interchanging the 2 and 6-substituents on the purine ring. Retreversine is inactive at 10-fold higher concentrations than reversine in the myoblast assay.1

Definition

ChEBI: Retreversine is a member of morpholines.

References

1. Chen, S., Zhang, Q., Wu, X., et al. Dedifferentiation of lineage-committed cells by a small molecule J. Am. Chem. Soc. 126(2),410-411(2004).

RETREVERSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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RETREVERSINE Suppliers

China 26 United States 1 Global 27
Shanghai Hongye Biotechnology Co. Ltd
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1028332-91-3, RETREVERSINERelated Search:


  • RETREVERSINE
  • 2-N-cyclohexyl-6-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine
  • 9H-Purine-2,6-diamine, N2-cyclohexyl-N6-[4-(4-morpholinyl)phenyl]-
  • 1028332-91-3