1,2-O-Isopropylidene-a-L-xylofuranose

Product Name: 1,2-O-Isopropylidene-a-L-xylofuranose
CAS No.: 114861-22-2
Chemical Name: 1,2-O-Isopropylidene-a-L-xylofuranose
Synonyms: SOTA-002;1,2-O-Isopropylidene-α-L-xylofuranose;1,2-O-Isopropylidene-L-D-xylofuranose;1,2-O-isopropylidene-α-L-xylofuranose;1,2-O-Isopropylidene-a-L-xylofuranose;1,2-O-Isopropylidene-alpha-L-xylofuranose;a-L-Xylofuranose,1,2-O-(1-methylethylidene)-;α-L-Xylofuranose, 1,2-O-(1-Methylethylidene)-;2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl Bromide;(3AS,5S,6R,6AS)-5-(HYDROXYMETHYL)-2,2-DIMETHYL-3A,5,6,6A-TETRAHYDROFURO[2,3-D][1,3]DIOXOL-6-OL
CBNumber: CB31231282
Molecular Formula: C8H14O5
Formula Weight: 190.19
MOL File: 114861-22-2.mol

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1,2-O-Isopropylidene-a-L-xylofuranose Property

Boiling point:: 333.0±37.0 °C(Predicted)
Density: 1.267±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 13.23±0.60(Predicted)
InChI: InChI=1/C8H14O5/c1-8(2)12-6-5(10)4(3-9)11-7(6)13-8/h4-7,9-10H,3H2,1-2H3/t4-,5+,6-,7-/s3
InChIKey: JAUQZVBVVJJRKM-TWULDSOMNA-N
SMILES: [C@H]12OC(C)(C)O[C@H]1[C@@H]([C@H](CO)O2)O |&1:0,6,7,8,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological

Product number: 293718
Product name: 1,2-O-Isopropylidene-a-L-xylofuranose
Packaging: 1g
Price: $375
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: O106876
Product name: 1-2-O-Isopropylidene-α-L-xylofuranose
Packaging: 1g
Price: $390
Updated: 2021/12/16

Biosynth Carbosynth

Product number: MI01012
Product name: 1,2-O-Isopropylidene-a-L-xylofuranose
Packaging: 10g
Price: $472.5
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: O106876
Product name: 1-2-O-Isopropylidene-α-L-xylofuranose
Packaging: 5G
Price: $663
Updated: 2021/12/16

AK Scientific

Product number: 5596CR
Product name: (3As,5S,6R,6aS)-5-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol
Packaging: 10g
Price: $687
Updated: 2021/12/16

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1,2-O-Isopropylidene-a-L-xylofuranose Chemical Properties,Usage,Production

Uses

1,2-O-Isopropylidene-a-L-xylofuranose can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly in laboratory research and development processes and chemical production processes.

Synthesis

((3aS,5R,6S,6aS)-6-Hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl)(morpholino)methanone (134). Step 1) (3aS,5S,6R,6aS)-5-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-6-ol. To a suspension of L-(-)-xylose (133, 19.15 g, 127.5 mmol) and MgSO4 (30.72 g, 255.0 mmol) in acetone (190 mL) was added conc. H2SO4 (1.9 mL) at room temperature. After 12 h, the reaction mixture (all L-(-)-xylose had been consumed) was filtered and the collected solids were washed with acetone (twice, 20 mL per wash). The stirring yellow filtrate was neutralized with NH4OH solution to pH ~ 9. The suspended solids were removed by filtration. The filtrate was concentrated to afford crude bis-acetonide intermediate as yellow oil. The yellow oil was suspended in water (5 mL), and then the pH was adjusted from 9 to 2 with 1 N HCl in water solution. The reaction mixture was stirred for 12 h at room temperature. The resulting mixture was neutralized by the addition of 25% (w/w) K3PO4 in water until pH ~ 7. The mixture was extracted with EtOAc. The organic layer was dried over MgSO4 filtered, and concentrated in vacuo. The crude product was purified by silica gel column chromatography. Yield: (12.63 g, 52%) as yellow oil. 1H NMR (400 MHz, CD3OD) δ 5.88 (d, J = 4.0 Hz, 1H), 4.47 (d, J 4.0 Hz, 1H), 4.18-4.14 (m, 1H), 4.1 1 (d, J = 2.8 Hz, 1H), 3.83-3.71 (m, 2H), 1.45 (s, 3H), 1.29 (s, 3H).

References

[1] RSC Advances, 2016, vol. 6, # 46, p. 39758 - 39761
[2] Tetrahedron, 1981, vol. 37, p. 1685 - 1690
[3] Patent: CN106892948, 2017, A. Location in patent: Paragraph 0188; 0189; 0190; 0191
[4] Helvetica Chimica Acta, 1938, vol. 21, p. 263,267
[5] Nucleosides, Nucleotides and Nucleic Acids, 2001, vol. 20, # 4-7, p. 703 - 706

1,2-O-Isopropylidene-a-L-xylofuranose Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-O-Isopropylidene-a-L-xylofuranose Suppliers

China 83 India 1 Ukraine 1 United Kingdom 2 United States 7 Global 94

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View Lastest Price from 1,2-O-Isopropylidene-a-L-xylofuranose manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1,2-O-Isopropylidene-α-L-xylofuranose 114861-22-2
Price: US $0.00/G
Min. Order: 1G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-21

Career Henan Chemical Co

Product: 1,2-O-Isopropylidene-a-L-xylofuranose 114861-22-2
Price: US $6.00/KG
Min. Order: 1KG
Purity: 95%-98%
Supply Ability: 100
Release date: 2019-09-04

114861-22-2, 1,2-O-Isopropylidene-a-L-xylofuranoseRelated Search:

Dikegulac sodium 2,3-O-Isopropylidene-1,6-ditosyl-L-sorbose Diacetone-D-glucose 2,5-ANHYDRO-1,3-O-ISOPROPYLIDENE-6-O-TRITYL-D-GLUCITOL 1,2-O-Isopropylidene-a-L-xylofuranose 1,2:3,5-Di-O-isopropylidene-alpha-D-xylofuranose Diacetone L-sorbose 2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonicacidmonohydrate DIKEGULAC ACID DIKEGULAC DIHYDRAT alpha-l-Sorbofuranose, 2,3-O-(1-methylethylidene)-

1,2-O-Isopropylidene-a-L-xylofuranose

1,2-O-Isopropylidene-alpha-L-xylofuranose

α-L-Xylofuranose, 1,2-O-(1-Methylethylidene)-

(3AS,5S,6R,6AS)-5-(HYDROXYMETHYL)-2,2-DIMETHYL-3A,5,6,6A-TETRAHYDROFURO[2,3-D][1,3]DIOXOL-6-OL

1,2-O-isopropylidene-α-L-xylofuranose

SOTA-002

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2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl Bromide

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1,2-O-Isopropylidene-α-L-xylofuranose

114861-22-2