ChemicalBook > CAS DataBase List > (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

Product Name
(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
CAS No.
4725-24-0
Chemical Name
(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
Synonyms
Cholesterol Impurity 34;7α,27-dihydroxycholesterol;cholest-5-ene-3,7,27-triol;7alpha,26-dihydroxycholesterol;7-alpha,27-Dihydroxycholesterol;Cholest-5-ene-3,7,26-triol, (3β,7α)-;(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
CBNumber
CB31235639
Molecular Formula
C27H46O3
Formula Weight
418.65
MOL File
4725-24-0.mol
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(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol Property

Boiling point:
552.6±35.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
storage temp. 
-20°C
pka
14.11±0.70(Predicted)
form 
powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
LIP0002865
Product name
7-ALPHA-27-DIHYDROXYCHOLESTEROL
Purity
95.00%
Packaging
5MG
Price
$495.34
Updated
2021/12/16
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(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol Chemical Properties,Usage,Production

Uses

7α,27-Dihydroxycholesterol is used in the study of immunochemistry. It is a potent and selective agonist of EB12.7α,27-Dihydroxycholesterol is also studied in biochemical methods as one of several oxysterols found in human plasma using HPLC-MS and incorporating charg-tagging and high-resolution mass spectrometry.

Definition

ChEBI: An oxysterol that is cholesterol which is substituted by hydroxy groups at the 7alpha and 26 positions.

Biological Activity

7α,27-dihydroxycholesterol (7α,27-di-OHC) is one of the metabolite screened in pathological conditions such as neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human specimens. Upon the lipopolysaccharide activation, the levels of 7α,27-di-OHC decreases.7α27-OHC is a ligand for Epstein-Barr virus-induced gene 2 (EBI2).

(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol Preparation Products And Raw materials

Raw materials

Preparation Products

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(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol Suppliers

China 7 United States 3 Global 10
ChemStrong Scientific Co.,Ltd
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4725-24-0, (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diolRelated Search:


  • (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
  • 7-alpha,27-Dihydroxycholesterol
  • cholest-5-ene-3,7,27-triol
  • 7alpha,26-dihydroxycholesterol
  • Cholest-5-ene-3,7,26-triol, (3β,7α)-
  • 7α,27-dihydroxycholesterol
  • Cholesterol Impurity 34
  • 4725-24-0