14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
- Product Name
- 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
- CAS No.
- 149402-51-7
- Chemical Name
- 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
- Synonyms
- Photochlor;Sulcardine;Photochlor (HTTP);Photochlor (HPPH);Photochlor Photochlor;Inhibitor,HPPH,inhibit;3-Devinyl-3-(1'-hexyloxy)ethylpyropheophorbide A;2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-4-phorbine propanoic acid;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
- CBNumber
- CB31238726
- Molecular Formula
- C39H48N4O4
- Formula Weight
- 636.82
- MOL File
- 149402-51-7.mol
14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid Property
- Boiling point:
- 992.5±65.0 °C(Predicted)
- Density
- 1.184
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO:3.0(Max Conc. mg/mL);4.7(Max Conc. mM)
- form
- A crystalline solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H370Causes damage to organs
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 20611
- Product name
- HPPH
- Purity
- ≥98% (mixture of epimers)
- Packaging
- 1mg
- Price
- $49
- Updated
- 2024/03/01
- Product number
- 20611
- Product name
- HPPH
- Purity
- ≥98% (mixture of epimers)
- Packaging
- 5mg
- Price
- $190
- Updated
- 2024/03/01
- Product number
- 20611
- Product name
- HPPH
- Purity
- ≥98% (mixture of epimers)
- Packaging
- 10mg
- Price
- $356
- Updated
- 2024/03/01
- Product number
- 20611
- Product name
- HPPH
- Purity
- ≥98% (mixture of epimers)
- Packaging
- 25mg
- Price
- $770
- Updated
- 2024/03/01
- Product number
- P365010
- Product name
- Photochlor
- Packaging
- 5mg
- Price
- $175
- Updated
- 2021/12/16
14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid Chemical Properties,Usage,Production
Description
HPPH is a chlorin that acts as a photosensitizer in photodynamic therapy (PDT) when stimulated with light at 655 nm. When administered systemically, HPPH accumulates in tumor cells and, when stimulated with light in the presence of oxygen, reactive oxygen species (ROS) are generated, leading to necrosis within the tumor. HPPH, at a dose of 0.5 mg/kg, increases survival in a nude rat model of glioma. It works synergistically with gemcitabine in several pancreatic cancer cell lines to induce cell death.
Uses
Photochlor is an anticancer photodynamic therapy drug that triggers multiple drug release and tumor killing cells in mouse breast cancer xenograft. Also functions as a photochlor-mediated photodynamic therapy for non-small cellular lung cancer treatment in murine model.
14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid manufacturers
- Product
- Photochlor Photochlor 149402-51-7
- Price
- US $10.00/g/Bag
- Min. Order
- 10g
- Purity
- 99
- Supply Ability
- 100KG
- Release date
- 2021-11-16
- Product
- 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid 149402-51-7
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02