14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid

Product Name: 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
CAS No.: 149402-51-7
Chemical Name: 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
Synonyms: Photochlor;Sulcardine;Photochlor (HTTP);Photochlor (HPPH);Photochlor Photochlor;Inhibitor,HPPH,inhibit;3-Devinyl-3-(1'-hexyloxy)ethylpyropheophorbide A;2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-4-phorbine propanoic acid;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid
CBNumber: CB31238726
Molecular Formula: C39H48N4O4
Formula Weight: 636.82
MOL File: 149402-51-7.mol

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14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid Property

Boiling point:: 992.5±65.0 °C(Predicted)
Density: 1.184
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO:3.0(Max Conc. mg/mL);4.7(Max Conc. mM)
form: A crystalline solid
color: Light brown to black

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

H341Suspected of causing genetic defects

H361Suspected of damaging fertility or the unborn child

H370Causes damage to organs

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20611
Product name: HPPH
Purity: ≥98% (mixture of epimers)
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 20611
Product name: HPPH
Purity: ≥98% (mixture of epimers)
Packaging: 5mg
Price: $190
Updated: 2024/03/01

Cayman Chemical

Product number: 20611
Product name: HPPH
Purity: ≥98% (mixture of epimers)
Packaging: 10mg
Price: $356
Updated: 2024/03/01

Cayman Chemical

Product number: 20611
Product name: HPPH
Purity: ≥98% (mixture of epimers)
Packaging: 25mg
Price: $770
Updated: 2024/03/01

TRC

Product number: P365010
Product name: Photochlor
Packaging: 5mg
Price: $175
Updated: 2021/12/16

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14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid Chemical Properties,Usage,Production

Description

HPPH is a chlorin that acts as a photosensitizer in photodynamic therapy (PDT) when stimulated with light at 655 nm. When administered systemically, HPPH accumulates in tumor cells and, when stimulated with light in the presence of oxygen, reactive oxygen species (ROS) are generated, leading to necrosis within the tumor. HPPH, at a dose of 0.5 mg/kg, increases survival in a nude rat model of glioma. It works synergistically with gemcitabine in several pancreatic cancer cell lines to induce cell death.

Uses

Photochlor is an anticancer photodynamic therapy drug that triggers multiple drug release and tumor killing cells in mouse breast cancer xenograft. Also functions as a photochlor-mediated photodynamic therapy for non-small cellular lung cancer treatment in murine model.

14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid Suppliers

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View Lastest Price from 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid manufacturers

Wuhan Demeikai Biotechnology Co., Ltd

Product: Photochlor Photochlor 149402-51-7
Price: US $10.00/g/Bag
Min. Order: 10g
Purity: 99
Supply Ability: 100KG
Release date: 2021-11-16

Career Henan Chemical Co

Product: 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid 149402-51-7
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

149402-51-7, 14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acidRelated Search:

Cephalosporin Azithromycin Cefaclor

Photochlor (HPPH)

3-Phorbinepropanoic acid, 14-ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18 -tetramethyl-20-oxo-, (3S,4S)-

Sulcardine

14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid

2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a

(3S,4S)-14-Ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid

3-Devinyl-3-(1'-hexyloxy)ethylpyropheophorbide A

Photochlor

Photochlor (HTTP)

14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-4-phorbine propanoic acid

Photochlor Photochlor

Inhibitor,HPPH,inhibit

149402-51-7

149402-51-8

C39H48N4O4