ChemicalBook > CAS DataBase List > Almokalant
Almokalant
- Product Name
- Almokalant
- CAS No.
- 123955-10-2
- Chemical Name
- Almokalant
- Synonyms
- H 234?/09;Almokalant;Benzonitrile, 4-[3-[ethyl[3-(propylsulfinyl)propyl]amino]-2-hydroxypropoxy]-
- CBNumber
- CB31244837
- Molecular Formula
- C18H28N2O3S
- Formula Weight
- 352.496
- MOL File
- 123955-10-2.mol
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Almokalant Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0009103
- Product name
- ALMOKALANT
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.46
- Updated
- 2021/12/16
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Almokalant Chemical Properties,Usage,Production
Uses
Almokalant is a class III antiarrhythmic agent, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current.
in vivo
Almokalant (125 μmol/kg, p.o.) induces cardiovascular defects, orofacial clefts, and tail defects in pregnant rats, after administration on Day 11. Almokalant also causes in pregnant rats[1].
References
[1] Wellfelt K, et al. Teratogenicity of the class III antiarrhythmic drug almokalant. Role of hypoxia and reactive oxygen species. Reprod Toxicol. 1999 Mar-Apr;13(2):93-101. DOI:10.1016/s0890-6238(98)00066-5
Almokalant Preparation Products And Raw materials
Raw materials
Preparation Products
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