methyl 2-(isocyanatosulfonylmethyl)benzoate Property

Boiling point:

427.2±55.0 °C(Predicted)

Density 

1.34±0.1 g/cm3(Predicted)

EPA Substance Registry System

Benzoic acid, 2-[(isocyanatosulfonyl)methyl]-, methyl ester (83056-32-0)

Safety

Hazard Codes 

Xn

Risk Statements 

10-14-20-41-42-48/22-68

Safety Statements 

23-26-36/37/39

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H318Causes serious eye damage

H332Harmful if inhaled

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H341Suspected of causing genetic defects

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P285In case of inadequate ventilation wear respiratory protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P314Get medical advice/attention if you feel unwell.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

methyl 2-(isocyanatosulfonylmethyl)benzoate Chemical Properties,Usage,Production

Chemical Properties

Oily liquid, soluble in xylene and acetonitrile.

Uses

Methyl 2-(isocyanatosulfonylmethyl)benzoate is an intermediate for the herbicide bensulfuron-methyl.

Synthesis

The preparation method is as follows: adding a mixture of n-butyl isocyanate and xylene into a reaction kettle, then adding o-methoxycarbonylbenzylsulfonamide, stirring, heating up to 120° C, passing through phosgene for 3 hours, sampling and analyzing, and the reaction is over. The phosgene is driven with nitrogen for about 1.5h, followed by distillation to recover n-butyl isocyanate and xylene, and the residual liquid is methyl 2-(isocyanatosulfonylmethyl)benzoate.