1,4-DIBROMO-2,3-DIFLUOROBENZENE
- Product Name
- 1,4-DIBROMO-2,3-DIFLUOROBENZENE
- CAS No.
- 156682-52-9
- Chemical Name
- 1,4-DIBROMO-2,3-DIFLUOROBENZENE
- Synonyms
- EA225;4-DIBROMO-2;1,4-Dibromo-2,3-difluorobenzene;2,3-Difluoro-1,4-dibromobenzene;Benzene,1,4-dibroMo-2,3-difluoro-;1,4-Dibromo-2,3-difluorobenzene 97%;1,4-Dibromo-2,3-difluorobenzene 95+%
- CBNumber
- CB31263548
- Molecular Formula
- C6H2Br2F2
- Formula Weight
- 271.88
- MOL File
- 156682-52-9.mol
1,4-DIBROMO-2,3-DIFLUOROBENZENE Property
- Boiling point:
- 212℃
- Density
- 2.087
- refractive index
- 1.5620-1.5660
- Flash point:
- 82℃
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- form
- clear liquid
- color
- Colorless to Red to Green
- InChI
- InChI=1S/C6H2Br2F2/c7-3-1-2-4(8)6(10)5(3)9/h1-2H
- InChIKey
- RGXGEFSBDPGCEU-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC=C(Br)C(F)=C1F
Safety
- HS Code
- 2903998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D4983
- Product name
- 1,4-Dibromo-2,3-difluorobenzene
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $44
- Updated
- 2025/07/31
- Product number
- D4983
- Product name
- 1,4-Dibromo-2,3-difluorobenzene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $150
- Updated
- 2025/07/31
- Product number
- D425340
- Product name
- 1,4-Dibromo-2,3-difluorobenzene
- Packaging
- 2.5g
- Price
- $1230
- Updated
- 2021/12/16
- Product number
- HCH0036615
- Product name
- 1,4-DIBROMO-2,3-DIFLUOROBENZENE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1947
- Updated
- 2021/12/16
- Product number
- J98983
- Product name
- 1,4-Dibromo-2,3-difluorobenzene
- Packaging
- 25g
- Price
- $265
- Updated
- 2021/12/16
1,4-DIBROMO-2,3-DIFLUOROBENZENE Chemical Properties,Usage,Production
Uses
1,4-Dibromo-2,3-difluorobenzene is a halogenated benzene used in the preparation of various biologically active compounds such as non-nucleoside reverse transcriptase inhibitors. 1,4-Dibromo-2,3-difluorobenzene is also used in the synthesis of conjugated polymers for organic photovoltaics.
Synthesis
867366-94-7
156682-52-9
1,4-Dibromo-2,3-difluorobenzene (5) was synthesized as follows: bromine (9.9 mL) was added to a 100 mL two-necked round-bottomed flask, which was connected to a condenser tube and a drying tube under ice bath conditions. Subsequently, 2,3-difluoro-1,4-bis(trimethylmethylsilyl)benzene (4.5 g, 19.34 mmol) was added, and the mixture was stirred at 58 °C for 1 hour. Next, another portion of bromine (0.5 mL) was added to the mixture and stirring was continued at the same temperature for 12 hours. Upon completion of the reaction, the mixture was cooled to 0 °C and the reaction was quenched by addition of sodium bicarbonate solution. The mixture was extracted with ethyl acetate and the organic phase was washed with brine and dried with magnesium sulfate. Subsequently, the solution was concentrated under vacuum using a rotary evaporator and the crude product was purified by column chromatography. The yield of the final product was 70%.
References
[1] Polymer, 2017, vol. 109, p. 115 - 125
[2] Journal of the American Chemical Society, 2015, vol. 137, # 32, p. 10420 - 10429
[3] Polymer, 2014, vol. 55, # 7, p. 1707 - 1715
[4] Patent: US2008/249151, 2008, A1. Location in patent: Page/Page column 16; 22-23
[5] Patent: US2006/25462, 2006, A1. Location in patent: Page/Page column 11; 20
1,4-DIBROMO-2,3-DIFLUOROBENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,4-DIBROMO-2,3-DIFLUOROBENZENE manufacturers
- Product
- 1,4-DIBROMO-2,3-DIFLUOROBENZENE 156682-52-9
- Price
- US $101.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-28
- Product
- 1,4-Dibromo-2,3-difluorobenzene 156682-52-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25