6-Benzothiazolecarbonitrile,2,3-dihydro-2-thioxo-(9CI)
- Product Name
- 6-Benzothiazolecarbonitrile,2,3-dihydro-2-thioxo-(9CI)
- CAS No.
- 315228-79-6
- Chemical Name
- 6-Benzothiazolecarbonitrile,2,3-dihydro-2-thioxo-(9CI)
- Synonyms
- 2-Mercaptobenzothiazole-6-carbonitrile;2-Mercaptobenzo[d]thiazole-6-carbonitrile;2-Mercapto-1,3-benzothiazole-6-carbonitrile;2,3-Dihydro-2-thioxo-6-benzothiazolecarbonitrile;6-Benzothiazolecarbonitrile, 2,3-dihydro-2-thioxo-;2-sulfanylidene-3H-1,3-benzothiazole-6-carbonitrile;6-Benzothiazolecarbonitrile,2,3-dihydro-2-thioxo-(9CI)
- CBNumber
- CB31272993
- Molecular Formula
- C8H4N2S2
- Formula Weight
- 192.26
- MOL File
- 315228-79-6.mol
6-Benzothiazolecarbonitrile,2,3-dihydro-2-thioxo-(9CI) Property
- Density
- 1.54
- storage temp.
- 2-8°C
- Appearance
- Light yellow to yellow Solid
N-Bromosuccinimide Price
- Product number
- CHM0093917
- Product name
- 2-MERCAPTOBENZOTHIAZOLE-6-CARBONITRILE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.48
- Updated
- 2021/12/16
- Product number
- A107565
- Product name
- 2-Mercaptobenzo[d]thiazole-6-carbonitrile
- Purity
- 96%
- Packaging
- 5g
- Price
- $524
- Updated
- 2021/12/16
- Product number
- CM131898
- Product name
- 2-mercaptobenzo[d]thiazole-6-carbonitrile
- Purity
- 96%
- Packaging
- 5g
- Price
- $688
- Updated
- 2021/12/16
- Product number
- CD11146752
- Product name
- 2-Mercaptobenzo[d]thiazole-6-carbonitrile
- Purity
- 96%
- Packaging
- 5g
- Price
- $728
- Updated
- 2021/12/16
- Product number
- 315228796
- Product name
- 2-Mercaptobenzo[d]thiazole-6-carbonitrile
- Packaging
- 5g
- Price
- $764.4
- Updated
- 2021/12/16
6-Benzothiazolecarbonitrile,2,3-dihydro-2-thioxo-(9CI) Chemical Properties,Usage,Production
Synthesis
140-89-6
33348-34-4
315228-79-6
The general procedure for the synthesis of 2-mercaptobenzothiazole-6-carbonitrile from potassium ethylxanthate and 4-amino-3-iodobenzonitrile was as follows: 4-amino-3-iodobenzonitrile (0.6 mmol), potassium ethylxanthate (1.8 mmol), FeF3 (0.06 mmol), 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl ( 0.03 mmol) and DMF (4 mL). The reaction vessel was replaced three times with argon and sealed. Subsequently, the mixture was placed in an oil bath at 110 °C and the reaction was electromagnetically stirred for 3-21 hours. The reaction process was monitored by silica gel thin layer chromatography (TLC). After completion of the reaction, the reaction mixture was cooled to room temperature, 4 mL of 3 mol/L hydrochloric acid solution was added and stirred for 30 min. The reaction mixture was extracted with ethyl acetate (3 x 20 mL). The organic phases were combined, dried with anhydrous sodium sulfate, and finally purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate) to obtain the target product 2-mercaptobenzothiazole-6-carbonitrile.
References
[1] Synthetic Communications, 2015, vol. 45, # 20, p. 2378 - 2385
[2] Phosphorus, Sulfur and Silicon and the Related Elements, 2016, vol. 191, # 5, p. 699 - 701
6-Benzothiazolecarbonitrile,2,3-dihydro-2-thioxo-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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