1H-Indole,2-chloro-(9CI)
- Product Name
- 1H-Indole,2-chloro-(9CI)
- CAS No.
- 7135-31-1
- Chemical Name
- 1H-Indole,2-chloro-(9CI)
- Synonyms
- 1H-Indole, 2-chloro-;1H-Indole,2-chloro-(9CI)
- CBNumber
- CB31278197
- Molecular Formula
- C8H6ClN
- Formula Weight
- 151.59
- MOL File
- 7135-31-1.mol
1H-Indole,2-chloro-(9CI) Property
- Melting point:
- 72-76 °C
- Boiling point:
- 293.0±13.0 °C(Predicted)
- Density
- 1.331±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- form
- Solid
- pka
- 15.40±0.30(Predicted)
- color
- Yellow
- Stability:
- Light Sensitive
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C364270
- Product name
- 2-Chloroindole
- Packaging
- 5g
- Price
- $390
- Updated
- 2021/12/16
- Product number
- X3503
- Product name
- 2-Chloroindole
- Packaging
- 1g
- Price
- $224
- Updated
- 2021/12/16
- Product number
- OR957032
- Product name
- 2-Chloroindole
- Purity
- 95%
- Packaging
- 1g
- Price
- $370
- Updated
- 2021/12/16
- Product number
- 3H32-5-MH
- Product name
- 2-Chloroindole
- Purity
- 95%
- Packaging
- 1g
- Price
- $592
- Updated
- 2021/12/16
- Product number
- CM232913
- Product name
- 2-Chloro-1H-indole
- Purity
- 95%
- Packaging
- 10g
- Price
- $645
- Updated
- 2021/12/16
1H-Indole,2-chloro-(9CI) Chemical Properties,Usage,Production
Uses
2-Chloroindole is used to prepare 2-pyrrolidinone derivatives as anticonvulsants.
Synthesis
59-48-3
7135-31-1
General procedure for the synthesis of 2-chloro-1H-indoles from 2-indolones: at room temperature, phosphorus oxychloride (POCl3, 1 mL, 10.82 mmol, 2 eq.) was slowly added to a well-stirred suspension of N,N-diethylaniline (1 mL, 5.41 mmol, 1 eq.) and 1,3-dihydro-2H-indol-2-one (0.72 g, 5.41 mmol , 1 equiv) in a suspension in anhydrous toluene (15 mL). The reaction mixture was heated to reflux for 3 hours. After completion of the reaction, it was cooled to room temperature and the reaction was quenched by careful addition of water (15 mL). The organic layer was separated and washed with water (3 x 25 mL). The organic layer was dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give 2-chloro-1H-indole (0.76 g, 93% yield) as an orange solid. The product was confirmed by LC-MS analysis ([M-H]-: 150/152).
References
[1] Patent: WO2006/128692, 2006, A2. Location in patent: Page/Page column 125; 126
1H-Indole,2-chloro-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-Indole,2-chloro-(9CI) manufacturers
- Product
- 1H-Indole,2-chloro-(9CI) 7135-31-1
- Price
- US $0.80-1.80/KG
- Min. Order
- 1KG
- Purity
- 95%~99.99%
- Supply Ability
- 10 MT/ Month
- Release date
- 2020-11-05