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1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI)

Product Name
1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI)
CAS No.
111851-98-0
Chemical Name
1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI)
Synonyms
1-ethylimidazole-2-carbaldehyde;1-ethyl-2-imidazolecarboxaldehyde;N-Ethyl-2-imidazolecarboxaldehyde;1-Ethylimidazole-2-carboxaldehyde;1-Ethylimidazole-2-carboxaldehyde,95%;1-Ethyl-1H-imidazole-2-carboxaldehyde;1H-IMidazole-2-carboxaldehyde, 1-ethyl-;1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI);1-ethyl-1H-imidazole-2-carbaldehyde(SALTDATA: FREE)
CBNumber
CB31297787
Molecular Formula
C6H8N2O
Formula Weight
124.14
MOL File
111851-98-0.mol
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1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI) Property

Boiling point:
258℃
Density 
1.10
Flash point:
110℃
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
form 
Solid
pka
4.29±0.31(Predicted)
Appearance
Light yellow to yellow Liquid
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Safety

HazardClass 
IRRITANT
HS Code 
2933299090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
B124748
Product name
1-Ethyl-1H-imidazole-2-carbaldehyde
Packaging
10mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
J94862
Product name
1-Ethyl-1H-imidazole-2-carbaldehyde
Packaging
250mg
Price
$20
Updated
2021/12/16
Apolloscientific
Product number
OR924988
Product name
1-Ethyl-1H-imidazole-2-carbaldehyde
Purity
95%
Packaging
1g
Price
$32
Updated
2021/12/16
Apolloscientific
Product number
OR924988
Product name
1-Ethyl-1H-imidazole-2-carbaldehyde
Purity
95%
Packaging
5g
Price
$68
Updated
2021/12/16
Apolloscientific
Product number
OR924988
Product name
1-Ethyl-1H-imidazole-2-carbaldehyde
Purity
95%
Packaging
10g
Price
$128
Updated
2021/12/16
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1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI) Chemical Properties,Usage,Production

Synthesis

75-03-6

10111-08-7

111851-98-0

To a suspension of 1H-imidazole-2-carbaldehyde (480 mg, 5 mmol) and anhydrous potassium carbonate (936 mg, 6 mmol) in N,N-dimethylformamide (7 mL) was added ethyl iodide (829 mg, 6 mmol). The reaction mixture was heated at 50 °C with stirring for 5 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was subjected to liquid-liquid partitioning with distilled water (30 mL) and ethyl acetate (30 mL). The aqueous phase was further extracted with ethyl acetate (20 mL x 3). All organic phases were combined, washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 1-ethyl-1H-imidazole-2-carbaldehyde as a light yellow oil (520 mg, 84% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 1.42-1.46 (t, J = 7.2 Hz, 3H), 4.42-4.47 (q, 2H), 7.19 (s, 1H), 7.29 (s, 1H), 9.82 (s, 1H). lC-MS (ESI) m/z: 125 (M + 1)+.

References

[1] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 2, p. 363 - 386
[2] Patent: US2010/35883, 2010, A1. Location in patent: Page/Page column 70-71
[3] Patent: EP1422228, 2004, A1. Location in patent: Page 223
[4] Patent: EP1550657, 2005, A1. Location in patent: Page/Page column 84
[5] Chemico-Biological Interactions, 2016, vol. 259, p. 85 - 92

1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI) Suppliers

Shanghai Hanhong Scientific Co.,Ltd.
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View Lastest Price from 1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI) manufacturers

Career Henan Chemical Co
Product
1H-Imidazole-2-carboxaldehyde,1-ethyl-(9CI) 111851-98-0
Price
US $5.50/KG
Min. Order
1KG
Purity
98%min
Supply Ability
1kg-100kg
Release date
2020-01-14