ara-ATP
- Product Name
- ara-ATP
- CAS No.
- 3714-60-1
- Chemical Name
- ara-ATP
- Synonyms
- ara-ATP;Arabino-ATP;ara-Adenosine-5'-triphosphate;ara-Adenosine-5'-triphosphate (ara-ATP);9-β-D-Arabinofuranosyl adenine 5′-triphosphate;Ara-adenosine-5'-triphosphate (ara-ATP) (aqueous solution);Adenine 9-β-D-arabinofuranoside 5′-triphosphate sodium salt;1-(6-Amino-9H-purin-9-yl)-1-deoxy-β-D-arabinofuranose 5-triphosphoric acid;9-[5-O-[[(Phosphonooxy)phosphonyloxy]phosphonyl]-β-D-arabinofuranosyl]-9H-purine-6-amine;Ara-adenosine-5''-triphosphate (ara-ATP) (aqueous solution), viral DNA polymerase inhibitor
- CBNumber
- CB31308726
- Molecular Formula
- C10H16N5O13P3
- Formula Weight
- 507.181023
- MOL File
- 3714-60-1.mol
ara-ATP Property
- Boiling point:
- 951.4±75.0 °C(Predicted)
- Density
- 2.63±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 0.97±0.50(Predicted)
Safety
- Hazard Codes
- T
- Risk Statements
- 63-23/24/25-36/37/38
- Safety Statements
- 22-36/37/39-45
ara-ATP Chemical Properties,Usage,Production
Enzyme inhibitor
This ATP and dATP analogue (FWfree-acid = 507.18 g/mol; CAS 3714-60-1), also known as 9-(5-O-(hydroxy(hydroxy(phosphonooxy) phosphinyl)phosphinyl)-b-D-arabinofuranosyl)-9H-purin-6-amine,Ara-ATP, adenine arabinoside 5’-triphosphate, and vidarabine 5’-triphosphate, is incorporated into viral DNA, thus inhibiting viral polymerase-mediated DNA synthesis via chain termination. Note: Some DNA polymerases are known to extend chains ending in the ara-nucleotide. Ara-ATP is available commercially for in vitro experimentation. Target(s): DNA primase; mRNA translocation; DNA-directed DNA polymerase; DNA polymerase a; DNA polymerase b; DNA polymerase g; ribonucleotide reductase; S-adenosylhomocysteine hydrolase; RNA polymerase; polynucleotide adenylyltransferase; GMP synthetase; lysyltRNA synthetase; leucyl-tRNA synthetase; adenylate cyclase; [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase, possible alternative substrate; duck hepatitis B virus reverse transcriptase; RNA-directed DNA polymerase; DNA nucleotidyl exotransferase, or terminal deoxyribonucleotidyl transferase.
ara-ATP Preparation Products And Raw materials
Raw materials
Preparation Products
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