ChemicalBook > CAS DataBase List > rabelomycin
rabelomycin
- Product Name
- rabelomycin
- CAS No.
- 28399-50-0
- Chemical Name
- rabelomycin
- Synonyms
- rabelomycin;(-)-3,4-Dihydro-3,6,8-trihydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione
- CBNumber
- CB31314660
- Molecular Formula
- C19H14O6
- Formula Weight
- 0
- MOL File
- 28399-50-0.mol
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rabelomycin Chemical Properties,Usage,Production
Description
Rabelomycin is an angucycline group antibiotic.
Uses
Rabelomycin is antibiotic, which exhibits antimicrobial activity against gram positive bacteria. Rabelomycin exhibits inhibitory activity against inducible nitric oxide synthase (iNOS) with an IC50 of 63.9 μM[1][2].
IC 50
iNOS: 63.9 μM (IC50)
References
[1] Kharel MK, et al., Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. Org Lett. 2010 Jun 18;12(12):2814-7. DOI:10.1021/ol1009009
[2] Alvi K A, et al., Identification of inhibitors of inducible nitric oxide synthase from microbial extracts[J]. The Journal of Antibiotics, 2000, 53(5): 496-501.
rabelomycin Preparation Products And Raw materials
Raw materials
Preparation Products
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