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YM 114

Product Name
YM 114
CAS No.
153608-99-2
Chemical Name
YM 114
Synonyms
YM 114;Kae 393
CBNumber
CB31317151
Molecular Formula
C16H18ClN3O
Formula Weight
303.79
MOL File
153608-99-2.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM1038454
Product name
YM 114
Purity
95.00%
Packaging
5MG
Price
$505.19
Updated
2021/12/16
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YM 114 Chemical Properties,Usage,Production

Description

YM 114 is a 5-HT(3) receptor anatagonist.

Uses

YM114 (KAE-393) is a highly potent and selective (5-HT)3-receptor antagonist that does not affect Veratridine (HY-N6691)- or electrical stimulation-induced bradycardia in anesthetized rats. YM114 inhibits 2-methyl-5-HT (HY-19358)-induced Bezold-Jarisch reflex, which originates from (5-HT)3-receptor located on the endings of vagal afferent nerves in the heart[1].

References

[1] Yamano M, et al. Characteristics of inhibitory effects of serotonin (5-HT)3-receptor antagonists, YM060 and YM114 (KAE-393), on the von Bezold-Jarisch reflex induced by 2-Methyl-5-HT, veratridine and electrical stimulation of vagus nerves in anesthetized rats. Jpn J Pharmacol. 1995 Dec;69(4):351-6. DOI:10.1254/jjp.69.351

YM 114 Preparation Products And Raw materials

Raw materials

Preparation Products

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YM 114 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
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United States
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32435
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Suzhou Meishi Biotechnology Co., Ltd.
Tel
1173954148q
Email
meishipharma@126.com
Country
China
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20033
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TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
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29423
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TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19962
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58