DU 717
- Product Name
- DU 717
- CAS No.
- 59943-31-6
- Chemical Name
- DU 717
- Synonyms
- DU 717;DU717, 10 mM in DMSO;7-Chloro-3-(4-methyl-1-piperazinyl)-4H-1,2,4-benzothiadiazine-1,1-dioxide;7-chloro-3-(4-methyl-1-piperazinyl)-2H-1,2,4-benzothiadiazine 1,1-dioxide;2H-1,2,4-Benzothiadiazine, 7-chloro-3-(4-methyl-1-piperazinyl)-, 1,1-dioxide
- CBNumber
- CB31327295
- Molecular Formula
- C12H15ClN4O2S
- Formula Weight
- 314.796
- MOL File
- 59943-31-6.mol
DU 717 Property
- Density
- 1.3907 (rough estimate)
- refractive index
- 1.5630 (estimate)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
N-Bromosuccinimide Price
- Product number
- HCH0172044
- Product name
- 7-CHLORO-3-(4-METHYL-1-PIPERAZINYL)-4H-1,2,4-BENZOTHIADIAZINE-1,1-DIOXIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.07
- Updated
- 2021/12/16
DU 717 Chemical Properties,Usage,Production
Uses
DU-717 is an antihypertensive agent.
in vivo
A gas chromatographic method has been developed which enables accurate determination of a new antihypertensive agent, DU-717, in plasma. Accurate determinations are possible over a concentration range from 10 to 150 ng/mL of DU-717 in plasma at a relative standard deviation of 6.2%. The minimum detectable concentration is 1 ng/mL. Plasma levels of DU-717 in spontaneously hypertensive and normotensive rats following single oral administrations (10 mg/kg) have also been determined[1].
References
[1] Yamaguchi T, et al. Determination of 7-chloro-3-(4-methyl-1-piperazinyl)-4h-1,2,4-benzothiadiazine-1,1-dioxide (DU-717) in plasma using electron-capture gas chromatography. J Chromatogr. 1978 Oct 11;160(1):181-90. DOI:10.1016/s0021-9673(00)91794-1
[2] R Horie. rats (ALR) and normotensive atherogenic rats (NAR).
DU 717 Preparation Products And Raw materials
Raw materials
Preparation Products
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