7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one
- Product Name
- 7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one
- CAS No.
- 4425-23-4
- Chemical Name
- 7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one
- Synonyms
- RLX;PD-139530;2,3-Pentanoquinazoline-4(3H)-one;VASICINONE HCl (Deoxydihomo-'c'-);7,8,9,10-Tetrahydro-6H-azepino[2,1-b]quinazolin-12-one;6,7,8,9,10,12-Hexahydroazepino[2,1-b]quinazoline-12-one;Azepino[2,1-b]quinazolin-12(6H)-one, 7,8,9,10-tetrahydro-
- CBNumber
- CB31339212
- Molecular Formula
- C13H14N2O
- Formula Weight
- 214.26
- MOL File
- 4425-23-4.mol
Safety
- HS Code
- 2933998090
- Toxicity
- LD50 oral in mouse: 1250mg/kg
N-Bromosuccinimide Price
- Product number
- CHM0156136
- Product name
- 7,8,9,10-TETRAHYDROAZEPINO[2,1-B]QUINAZOLIN-12(6H)-ONE
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $597.89
- Updated
- 2021/12/16
- Product number
- CHM0156136
- Product name
- 7,8,9,10-TETRAHYDROAZEPINO[2,1-B]QUINAZOLIN-12(6H)-ONE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $631.85
- Updated
- 2021/12/16
- Product number
- CHM0156136
- Product name
- 7,8,9,10-TETRAHYDROAZEPINO[2,1-B]QUINAZOLIN-12(6H)-ONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $633.99
- Updated
- 2021/12/16
- Product number
- M1607
- Product name
- 7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one
- Purity
- 97.00%
- Packaging
- 1G
- Price
- $1950
- Updated
- 2021/12/16
- Product number
- M1607
- Product name
- 7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one
- Purity
- 97.00%
- Packaging
- 5G
- Price
- $3300
- Updated
- 2021/12/16
7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one Chemical Properties,Usage,Production
Uses
RLX (PD 139530) is a PI3K/Akt/FoxO3a signaling inhibitor, possessing significant therapeutic potential in experimental colon cancer. RLX can effectively modulate the tumor microenvironment, enhancing the efficacy of cancer immunotherapy. RLX demonstrates the ability to improve the retention time of therapeutic agents within the tumor microenvironment by utilizing advanced nanoparticle delivery systems. RLX can be integrated with various treatment modalities, such as chemotherapy and radiotherapy, to enhance overall tumor therapy effectiveness. RLX highlights the necessity for further research into the tumor microenvironment’s dynamics to develop more tailored treatment approaches for diverse tumor types.
References
[1] The application of nanoparticles in cancer immunotherapy: Targeting tumor microenvironment
7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one Suppliers
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