ChemicalBook > CAS DataBase List > 7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one

7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one

Product Name
7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one
CAS No.
4425-23-4
Chemical Name
7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one
Synonyms
RLX;PD-139530;2,3-Pentanoquinazoline-4(3H)-one;VASICINONE HCl (Deoxydihomo-'c'-);7,8,9,10-Tetrahydro-6H-azepino[2,1-b]quinazolin-12-one;6,7,8,9,10,12-Hexahydroazepino[2,1-b]quinazoline-12-one;Azepino[2,1-b]quinazolin-12(6H)-one, 7,8,9,10-tetrahydro-
CBNumber
CB31339212
Molecular Formula
C13H14N2O
Formula Weight
214.26
MOL File
4425-23-4.mol
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Safety

HS Code 
2933998090
Toxicity
LD50 oral in mouse: 1250mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0156136
Product name
7,8,9,10-TETRAHYDROAZEPINO[2,1-B]QUINAZOLIN-12(6H)-ONE
Purity
95.00%
Packaging
1MG
Price
$597.89
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0156136
Product name
7,8,9,10-TETRAHYDROAZEPINO[2,1-B]QUINAZOLIN-12(6H)-ONE
Purity
95.00%
Packaging
10MG
Price
$631.85
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0156136
Product name
7,8,9,10-TETRAHYDROAZEPINO[2,1-B]QUINAZOLIN-12(6H)-ONE
Purity
95.00%
Packaging
5MG
Price
$633.99
Updated
2021/12/16
AccelPharmtech
Product number
M1607
Product name
7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one
Purity
97.00%
Packaging
1G
Price
$1950
Updated
2021/12/16
AccelPharmtech
Product number
M1607
Product name
7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one
Purity
97.00%
Packaging
5G
Price
$3300
Updated
2021/12/16
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7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one Chemical Properties,Usage,Production

Uses

RLX (PD 139530) is a PI3K/Akt/FoxO3a signaling inhibitor, possessing significant therapeutic potential in experimental colon cancer. RLX can effectively modulate the tumor microenvironment, enhancing the efficacy of cancer immunotherapy. RLX demonstrates the ability to improve the retention time of therapeutic agents within the tumor microenvironment by utilizing advanced nanoparticle delivery systems. RLX can be integrated with various treatment modalities, such as chemotherapy and radiotherapy, to enhance overall tumor therapy effectiveness. RLX highlights the necessity for further research into the tumor microenvironment’s dynamics to develop more tailored treatment approaches for diverse tumor types.

References

[1] The application of nanoparticles in cancer immunotherapy: Targeting tumor microenvironment

7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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7,8,9,10-tetrahydroazepino(2,1-b)quinazolin-12(6H)-one Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
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United States
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32435
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TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
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China
ProdList
29357
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Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
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58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19961
Advantage
58