BIBN 4096BS

Product Name: BIBN 4096BS
CAS No.: 204697-65-4
Chemical Name: BIBN 4096BS
Synonyms: BIBN-4096;Olcegepant;BIBN 4096BS;Olcegepant（ BIBN-4096）;Olcegepant, 10 mM in DMSO;BIBN 4096BS API Olcegepant;Olcegepant, CGRP antagonist;Olcegepant/BIBN-4096/BIBN 4096BS;inhibit,BIBN4096,Olcegepant,CGRP Receptor,Calcitonin gene-related peptide receptor,BIBN 4096,Inhibitor;1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)-piperazine
CBNumber: CB31346269
Molecular Formula: C38H47Br2N9O5
Formula Weight: 869.65
MOL File: 204697-65-4.mol

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BIBN 4096BS Property

Boiling point:: 1091.9±65.0 °C(Predicted)
Density: 1.497
storage temp.: Store at -20°C
solubility: ≥87 mg/mL in DMSO with gentle warming; insoluble in EtOH; insoluble in H2O
form: Powder
pka: 6.80±0.25(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 4561
Product name: BIBN4096
Purity: ≥95%(HPLC)
Packaging: 10
Price: $338
Updated: 2021/12/16

TRC

Product number: O516000
Product name: Olcegepant
Packaging: 1mg
Price: $235
Updated: 2021/12/16

Usbiological

Product number: 018736
Product name: Olcegepant
Packaging: 10mg
Price: $566
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 52600
Product name: Olcegepant
Packaging: 10mg
Price: $725
Updated: 2021/12/16

ApexBio Technology

Product number: A3680
Product name: Olcegepant
Packaging: 50mg
Price: $1129
Updated: 2021/12/16

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BIBN 4096BS Chemical Properties,Usage,Production

Uses

Olcegepant is a potent and selective calcitonin gene-related peptide (CGRP) receptor antagonist. Olcegepant displays high affinity for human CGRP receptors and exhibits no significant affinity for 75 other receptors. Olcegepant may a be viable option for the treatment of acute migraines.

Biological Activity

BIBN4096BS (Olcegepant) is a potent calcitonin gene-related peptide (CGRP) receptor antagonist with higher affinity/potency toward human over r at & mouse receptor (human/r at Ki = 14.4 pM/3.4 nM by binding assay; human/mouse Kb = 8 pM//7.711 nM by cellular cAMP assay). BIBN4096BS inhibits facial blood flow by electrical stimulation of marmoset monkey trigeminal ganglion (IC50 = 3 μg/kg i.v.) without any intrinsic cardiovascular effects. Studies using anaesthetized rats reveals th at BIBN4096BS antagonism against trigeminal nociceptive stimulation by capsaicin is limited to the spinal trigeminal nucleus, but not trigeminal ganglion. Also widely employed for in vivo studies in mice.

target

CGRP1

storage

Store at -20°C

BIBN 4096BS Preparation Products And Raw materials

Raw materials

Preparation Products

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BIBN 4096BS Suppliers

Canada 2 China 57 India 1 United Kingdom 1 United States 13 Global 74

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
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Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
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Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 18017383231 18017383231
Fax: qq：2817624287
Email: lyh_antaeus@163.com
Country: China
ProdList: 9347
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4566
Advantage: 55

DKMbiochem.Co. Ltd

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Fax: 15901859516
Email: sales@DKMbiochem.com
Country: China
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LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
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Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4589
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SPIRO PHARMA

Tel
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Email: eric_feng1954@126.com
Country: China
ProdList: 9248
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Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 17687
Advantage: 55

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View Lastest Price from BIBN 4096BS manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Olcegepant 204697-65-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Olcegepant 204697-65-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

204697-65-4, BIBN 4096BSRelated Search:

5-DIMETHYLAMINO-1-NAPHTHALENESULFONIC ACID HYDRATE Sulfanilamide

BIBN 4096BS

BIBN-4096

N-[2-[5-Amino-1(S)-[4-(4-pyridinyl)piperazin-1-ylcarbonyl]pentylamino]-1(R)-(3,5-dibromo-4-hydroxybenzyl)-2-oxoethyl]-4-(2-oxo-1,2,3,4-tetrahydroquinazolin-3-yl)piperidine-1-carboxamide

Olcegepant

1-[3,5-Dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)-piperazine

BIBN 4096BS API Olcegepant

Piperazine, 1-[3,5-dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)-

Olcegepant（ BIBN-4096）

inhibit,BIBN4096,Olcegepant,CGRP Receptor,Calcitonin gene-related peptide receptor,BIBN 4096,Inhibitor

Olcegepant/BIBN-4096/BIBN 4096BS

Olcegepant, CGRP antagonist

Olcegepant, 10 mM in DMSO

204697-65-4

C38H47Br2N9O5