p2Ca peptide

Product Name: p2Ca peptide
CAS No.: 142606-55-1
Chemical Name: p2Ca peptide
Synonyms: p2Ca;p2Ca peptide;H-Leu-Ser-Pro-Phe-Pro-Phe-Asp-Leu-OH;L-Leucine, L-leucyl-L-seryl-L-prolyl-L-phenylalanyl-L-prolyl-L-phenylalanyl-L-α-aspartyl-
CBNumber: CB31359889
Molecular Formula: C47H66N8O12
Formula Weight: 935.07
MOL File: 142606-55-1.mol

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p2Ca peptide Property

Boiling point:: 1307.2±65.0 °C(Predicted)
Density: 1.298±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 3.24±0.10(Predicted)
Water Solubility: Soluble in Water
Sequence: Leu-Ser-Pro-Phe-Pro-Phe-Asp-Leu

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Hazard and Precautionary Statements (GHS)

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p2Ca peptide Chemical Properties,Usage,Production

Uses

p2Ca, an 8-mer peptide, is a ligand that is naturally processed and presented to the Ld-alloreactive T cell clone, 2C.

in vivo

BALB/c mice, coinjected with a syngeneic BALB/c myeloma and exogenous p2Ca, are able to reject the tumor. The p2Ca/L d system may thus provide a model for evaluating the parameters for effective immunotherapy with tumor-associated peptides^[3].

References

[1] Hornell TM, et al. Peptide length variants p2Ca and QL9 present distinct conformations to L(d)-specific T cells. J Immunol. 2001 Oct 15;167(8):4207-14. DOI:10.4049/jimmunol.167.8.4207
[2] Connolly JM, et al. The peptide p2Ca is immunodominant in allorecognition of Ld by beta chain variable region V beta 8+ but not V beta 8- strains. Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11482-6. DOI:10.1073/pnas.91.24.11482
[3] Tjoa BA, et al. Generation of cytotoxic T-lymphocytes to a self-peptide/class I complex: a model for peptide-mediated tumor rejection. Cancer Res. 1994 Jan 1;54(1):204-8. PMID:7505197

p2Ca peptide Preparation Products And Raw materials

Raw materials

Preparation Products

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p2Ca peptide Suppliers

China 34 United States 5 Global 39

MedChemexpress LLC

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Career Henan Chemica Co

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Nanjing TGpeptide Biotechnology Co.,Ltd.

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142606-55-1, p2Ca peptideRelated Search:

p2Ca peptide

H-Leu-Ser-Pro-Phe-Pro-Phe-Asp-Leu-OH

L-Leucine, L-leucyl-L-seryl-L-prolyl-L-phenylalanyl-L-prolyl-L-phenylalanyl-L-α-aspartyl-

p2Ca

142606-55-1

C47H66N8O12