ChemicalBook > CAS DataBase List > 1,4,8,11-TETRAAZACYCLOTETRADECANE

1,4,8,11-TETRAAZACYCLOTETRADECANE

Product Name
1,4,8,11-TETRAAZACYCLOTETRADECANE
CAS No.
295-37-4
Chemical Name
1,4,8,11-TETRAAZACYCLOTETRADECANE
Synonyms
CYCLAM;jm1498;Cyclam, 98+%;otetradecane;Compound PDK0168;Valine Impurity 134;1,4,8,11-TetraazacycL;Plerixafor Impurity 67;cyclaM, Methanol adduct;Plerixafor intermediate
CBNumber
CB3136889
Molecular Formula
C10H24N4
Formula Weight
200.32
MOL File
295-37-4.mol
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1,4,8,11-TETRAAZACYCLOTETRADECANE Property

Melting point:
184-186 °C (lit.)
Boiling point:
328.07°C (rough estimate)
Density 
1.0203 (rough estimate)
refractive index 
1.5200 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Dichloromethane, Methanol
pka
10.90±0.20(Predicted)
form 
Fluffy Needle-Like Crystalline Powder
color 
White
Water Solubility 
Soluble in water.
Sensitive 
Air Sensitive
BRN 
111811
InChIKey
MDAXKAUIABOHTD-UHFFFAOYSA-N
CAS DataBase Reference
295-37-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
XA5254800
F 
3-9-34
HS Code 
29339900
Toxicity
LD50 intraperitoneal in mouse: 371mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
259160
Product name
1,4,8,11-Tetraazacyclotetradecane
Purity
98% (GC)
Packaging
1g
Price
$79.8
Updated
2024/03/01
Sigma-Aldrich
Product number
259160
Product name
1,4,8,11-Tetraazacyclotetradecane
Purity
98% (GC)
Packaging
5g
Price
$194
Updated
2024/03/01
TCI Chemical
Product number
T1597
Product name
1,4,8,11-Tetraazacyclotetradecane
Purity
>98.0%(T)
Packaging
1g
Price
$91
Updated
2024/03/01
TCI Chemical
Product number
T1597
Product name
1,4,8,11-Tetraazacyclotetradecane
Purity
>98.0%(T)
Packaging
5g
Price
$302
Updated
2024/03/01
Alfa Aesar
Product number
A11516
Product name
1,4,8,11-Tetraazacyclotetradecane, 98+%
Packaging
1g
Price
$65.65
Updated
2024/03/01
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1,4,8,11-TETRAAZACYCLOTETRADECANE Chemical Properties,Usage,Production

Chemical Properties

white fluffy needle-like crystalline powder

Uses

Reagent used in the preparation of Plerixafor derivatives.

Uses

1,4,8,11-Tetraazacyclotetradecane is macrocyclic ligand that is used as an antioxidant in rubber and has been shown to suppress oxidation catalyzed by some metal ions.

Uses

1,4,8,11-Tetraazacyclotetradecane is used in the synthesis of molecules with electroactive cavities. It acts as a nitrogen crown ether analogue and as an antioxidant in rubber. It is also used in the preparation of plerixafor derivatives.

Definition

ChEBI: 1,4,8,11-tetraazacyclotetradecane is a saturated organic heteromonocyclic parent, a crown amine and an azacycloalkane. It derives from a hydride of a cyclotetradecane.

General Description

1,4,8,11-Tetraazacyclotetradecane is an azamacrocycle that forms more stable metal complexes as compared to open chain ligands.

Purification Methods

Purify cyclam by recrystallisation from dioxane (white needles), and it sublimes above 120o. It has been distilled, b 132-140o/4-8mm. It forms complexes with metals and gives a sparingly soluble nitrate salt, m 205o(dec), which crystallises from H2O and is dried at 150o. [UV: Bosnich et al. Inorg Chem 4 1102 1963, van Alphen Recl Trav Chim Pays-Bas 56 343 1937, Beilstein 26 III/IV 1647.]

1,4,8,11-TETRAAZACYCLOTETRADECANE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,4,8,11-TETRAAZACYCLOTETRADECANE Suppliers

Belgium 3 Canada 1 China 221 Czech 1 Czech Republic 1 France 2 Germany 8 India 31 Japan 5 Slovakia 1 South Korea 1 Switzerland 3 Ukraine 1 United Kingdom 17 United States 27 Global 323
CHEMOS GmbH & Co. KG
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chemos@chemos.de
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Germany
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6727
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58
Merck Millipore
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ccc@merckgroup.com
Country
Germany
ProdList
2008
Advantage
58
Alfa Aesar, Thermo Fisher Scientific
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es@alfa.com
Country
Germany
ProdList
5123
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58
ChemPur GmbH
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info@ChemPur.de
Country
Germany
ProdList
2737
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Trigona oHG
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info@trigona.de
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Germany
ProdList
614
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ABCR GmbH & CO. KG
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info@abcr.de
Country
Germany
ProdList
6831
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Service Chemical Inc.
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sales@chemos-group.com
Country
Germany
ProdList
6350
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Merck Schuchardt OHG
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schuchardt-vertrieb@merck.de
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Germany
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View Lastest Price from 1,4,8,11-TETRAAZACYCLOTETRADECANE manufacturers

Wuhan Boye Science And Technology Development Co., Ltd.
Product
1,4,8,11-Tetraazacyclotetradecane 295-37-4
Price
US $3840.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
5 tons
Release date
2021-03-23
Zhuozhou Wenxi import and Export Co., Ltd
Product
1,4,8,11-Tetraazacyclotetradecane 98% (GC) 295-37-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
1,4,8,11-TETRAAZACYCLOTETRADECANE 295-37-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-03-05

295-37-4, 1,4,8,11-TETRAAZACYCLOTETRADECANERelated Search:

Plerixafor 8HCl (AMD3100 8HCl) 1,4,8-Tri-Boc-1,4,8,11-tetraazacyclotetradecane 1,4,8,11-Tetrakis(dimethylaminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane 1,4,8,11-Tetrakis(aminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane,1,4,8,11-Tetraazacyclotetradecane-N,N',N'',N'''-tetraacetamide, min. 98% 1,4,8,11-Tetrakis(diethylaminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane 1,8-Dibenzyl-1,4,8,11-tetraazacyclotetradecane 1-Benzyl-1,4,8,11-tetraazacyclotetradecane,N-Benzyl-1,4,8,11-tetraazacyclotetradecane, min. 98% 1,4,8,11-Tetramethyl-1,4,8,11-tetraazacyclotetradecane,98%,1,4,8,11-TETRAMETHYL-1,4,8,11-TETRAAZACYCLOTETRADECANE 1,4,8,11-TETRAAZACYCLOTETRADECANE CIS-1,4,8,11-PERHYDROTETRAAZAPYRENE 1,4,8-Tris(aminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane monohydriodide 1,4,8,11-Tetrakis(ethoxycarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane Tetradecane 1,4,8,11-TETRAAZA-CYCLOTETRADECANE-5,12-DIONE 1,4,8,11-TETRAAZACYCLOTETRADECANE-5,7-DIONE 1,4,8,11-TETRAAZACYCLOTETRADECANE-1,4,8,11-TETRAACETIC ACID TETRAHYDROCHLORIDE HYDRATE 1 8-DIMETHYL-1 4 8 11-TETRAAZACYLCO- 1,1'-[1,3-PHENYLENEBIS-(METHYLENE)]-BIS-(1,4,8,11-TETRAAZACYCLOTETRADECANE) OCTAHYDROCHLORIDE

  • 1,4,8-Tris(trifluoroacetyl)-1,4,8,11-tetraazacyclotetradecane
  • 1,4,8-Tris(trifluoroacetyl)cyclaM
  • cyclaM, Methanol adduct
  • 1,4,8,11-Tetraazacyclotetradecane 98% (GC)
  • jm1498
  • CYCLAM
  • Cyclam, 98+%
  • 1,4,8,11-TETRAAZACYCLOTETRADECANE
  • Cyclam=1,4,8,11-Tetraazacyclotetradecane
  • 1,4,8,11-Tetraazacyclotetradecane, 99+%
  • 1,4,8,11-Tetraazacyclotetradecane,min.98%CYCLAM
  • 1,4,8,11-TETRAAZACYCLOTETRADECANE(CYCLAM)
  • 1,4,8,11-Tetraazacyclotetradecane 98%
  • 1,4,8,11-TETRAAZACYCLOTETRADECANE, 98+%
  • (1α,4β,8β,11α)-1,4,8,11-Tetraazacyclotetradecane
  • 1,4,8,11-tetraazacyclotetradecane Hexa(trifluoroacetate)
  • 1,1',1''-(1,4,8,11-Tetraazacyclotetradecane-1,4,8-triyl)tris[2,2,2-trifluoro-ethanone
  • 1,4,8,11-Tetraazacyclotetradecane, 99+% 1GR
  • Tetraazacyclotetradecane
  • 1,4,8,11-TetraazacycL
  • otetradecane
  • 1,4,8,11-tetrazacyclotetradecane
  • Plerixafor 1,4,8,11-Tetraazacyclotetradecane
  • Plerixafor intermediate
  • Plerixafor 1,4,8,11-Tetraazacyclotetradecane/ 1,4,8,11-Tetraazacyclotetradecane
  • (1α,4β,8β,11α)-1,4,8,11-Tetraazacyclotetradecane
  • 1,4,8,11-TETRAAZACYCLOTETRADECANE 295-37-4
  • 1,4,8,11-Tetraazacyclotetradecane (6CI, 7CI, 8CI, 9CI, ACI)
  • Compound PDK0168
  • Plerixafor Impurity 67
  • Valine Impurity 134
  • 295-37-4
  • C10H20N4
  • C10H24N4
  • C16H21F9N4O3
  • Synthetic Reagents
  • Macrocycles for Host-Guest Chemistry
  • Azacrown Ethers
  • Crown Ethers
  • Chelation/Complexation Compounds
  • Ring Systems
  • organic amine
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Azacrown Ethers
  • Crown Ethers
  • Functional Materials
  • Macrocycles for Host-Guest Chemistry
  • Achiral Nitrogen
  • Cy-N